66064-61-7Relevant academic research and scientific papers
A study on the friedel-crafts type reaction of ninhydrin with arenes
Song, Hyun Nam,Seong, Mi Ra,Son, Ji Suk,Kim, Jae Nyoung
, p. 1865 - 1870 (1998)
The reactions of ninhydrin (1, 1,2,3-indantrione) with arenes in the presence of concentrated sulfuric acid afforded mono- or di-substituted ninhydrin derivatives at the 2-position in reasonable yields.
A convenient synthesis of 4-diarylmethyl-, 4-(α-hydroxy- α-aryl/naphthyl)methyl- and 4-(benzoyl/naphthanoyl)-1-(2H)-phthalazinones from ninhydrin
Kundu, Sandip Kumar,Pramanik, Animesh
, p. 595 - 603 (2007/10/03)
Refluxing of 2,2-diaryl-1,3-indanediones in hydrazine hydrate for a brief period affords 4-diarylmethyl-1-(2H) phthalazinones in very high yield. A series of 4-(α-hydroxy-α-aryl/naphthyl)methyl- and 4-(benzoyl/naphthanoyl)-1-(2H) phthalazinones also have
Facile acid-catalyzed condensation of ninhydrin with enols and aromatic compounds and microwave enhanced condensation of ninhydrin with hydroxy aromatic systems in solid state
Kundu, Sandip Kumar,Patra, Amarendra,Pramanik, Animesh
, p. 604 - 611 (2007/10/03)
Di- and trihydroxybenzenes, 2,6-dihydroxyacetophenone, α- and β-naphthols and also 3- and 4-hydroxycoumarins and various enols smoothly condense with ninhydrin in HOAc medium giving 2-substituted 1,3-dioxoindanes. Monoarylated products were also obtained
