660838-99-3

Upstream product

• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 53933-45-2 (S)-1-Methoxycarbonyl-2-phenylethylhydroxylamine 
• 73995-67-2 (S)-2-[3-(4-Methoxy-phenyl)-oxaziridin-2-yl]-3-phenyl-propionic acid methyl ester 

Relevant academic research and scientific papers

Synthesis of chiral azomethines from methyl l-3-phenylalaninate hydrochloride and substituted benzaldehydes of vanillin series

A preparative procedure is developed for the synthesis of chiral azomethines from methyl L-3-phenylalaninate and substituted aldehydes of vanillin series.

Highly Stereoselective Synthesis of Optically Pure C-Aryl Imines from α-L-Amino Acid Methyl Esters

The title compounds were easily synthesized starting from readily available α-L-amino acid methyl esters in excellent overall yields. The key feature of the methodology here reported was the TiCl4 mediated condensation of the 4-methoxybenzaldeh

Process for producing alpha-aminoketones

An amino group of an α-amino acid ester is protected as an imine, and it is then reacted with a halomethyllithium to obtain an N-protected-α-aminohalomethylketone. Further, this N-protected-α-aminohalomethylketone is treated with an acid to obtain an α-aminohalomethylketone. This process is suited for industrial production, and can produce an α-aminohalomethylketone and its related compounds economically and efficiently.