66134-68-7Relevant academic research and scientific papers
One-pot synthesis of hydroxamic acids from aldehydes and hydroxylamine
Dettori, Giovanna,Gaspa, Silvia,Porcheddu, Andrea,De Luca, Lidia
supporting information, p. 2709 - 2713 (2014/09/17)
A one-pot oxidative transformation of aldehydes into hydroxamic acids by the use of an aqueous solution of hydroxylamine is reported. The methodology gives high yields and makes use of cheap, abundant and easily available reagents.
Iodide-catalyzed amide synthesis from alcohols and amines
Wang, Gao,Yu, Qing-Ying,Wang, Jian,Wang, Shan,Chen, Shan-Yong,Yu, Xiao-Qi
, p. 21306 - 21310 (2013/11/06)
An efficient method to prepare amides by a cascade strategy was developed. Using nBu4NI or NaI as the catalyst and tert-butyl hydroperoxide as the oxidant, various alcohols reacted with N-hydroxysuccinimide or N-hydroxyphthalimide affording corresponding active esters in moderate to good yield. The resulting active esters were converted into amides smoothly in one pot. The Royal Society of Chemistry 2013.
A copper-catalysed amidation of aldehydes via N-hydroxysuccinimide ester formation
Pilo, Monica,Porcheddu, Andrea,De Luca, Lidia
, p. 8241 - 8246 (2013/12/04)
A copper-catalysed oxidative amidation of aldehydes via N-hydroxysuccinimide ester formation is reported. The methodology employed to prepare amides directly from aldehydes has a very wide scope, is high yielding, and does not need dry conditions. This cross-coupling reaction appears to be simple and makes use of cheap, abundant and easily available reagents.
Convenient synthesis of N-hydroxysuccinimide esters from carboxylic acids using triphosgene
Kim, Misoo,Han, Ki-Jong
experimental part, p. 4467 - 4472 (2010/05/01)
A simple and convenient method for the synthesis of N-hydroxysuccinimide ester is developed using triphosgene as an acid activator. Several aromatic and aliphatic N-hydroxysuccinimide esters are prepared from their corresponding carboxylic acids at room temperature in good yields in a rapid process using triphosgene. Some of the major advantages are mild conditions, good yields, and easy operation.
N-hydroxysuccinimide-promoted oxidation of primary alcohols and aldehydes to form active esters with hypervalent(III) iodine
Wang, Naiwei,Liu, Renhua,Xu, Qing,Liang, Xinmiao
, p. 566 - 567 (2007/10/03)
A simple, mild, and efficient method for the conversion of primary alcohols and aldehydes to N-hydroxysuccinimide esters with (diacetoxyiodo)benzene in high yield is developed. N-Hydroxysuccinimide acts not only as an esterification partner but also as an activator of PhI(OAc)2 in this reaction. Copyright
