66166-18-5Relevant academic research and scientific papers
Acid controlled generation of indanes and oxazolines from β-hydroxyarylethanamide
Suresh, Rajendran,Muthusubramanian, Shanmugam,Boominathan, Muthusamy,Manickam, Govindaswamy
supporting information, p. 2315 - 2320 (2013/06/26)
Simple and efficient protocols for the construction of substituted indanes and oxazolines through intramolecular cyclization of β- hydroxyarylethanamide using trifluoromethanesulfonic acid and titanium tetrachloride in 1,2-dichloroethane respectively have
Physical Aspects of N-Benzoylaziridine Photochemistry. Characterization of Azomethine Ylides and Related Photointermediates
Ramaiah, D.,Cyr, D. R.,Barik, R.,Gopidas, K. R.,Das, P. K.,George, M. V.
, p. 1271 - 1278 (2007/10/02)
Results of a time-resolved study based on nanosecond laser flash photolysis are presented for phototransients derived from three N-benzoylaziridines in fluid solutions.The major transients, best assigned as azomethine ylides, are characterized by two maxima (380 - 440 and 560 - 610 nm) in the absorption spectrum in the visible region and by microsecond lifetimes at room temperature (τY = 0.2 - 31 μs); these are sluggish in their reactivity toward dimethyl acetylenedicarboxylate kqY 4 M-1 s-1 in benzene).Relatively short-lived triplets (τT = 1-90 ns in benzene) quenchable by biphenyl and 2,5-dimethyl-2,4-hexadiene, act as precursors for the ylides.Between trans-1-benzoyl-2,3-diphenylaziridine (1a) and its cis isomer (1b), τT is considerably shorter for the former (1 ns for 1a vs 40 ns for 1b, on the basis of the assumption that the rate constant for triplet quenching by 2,5-dimethyl-2,4-hexadiene is 2 * 109 M-1 s-1 in benzene); this is explainable in terms of efficient intramolecular quenching of the benzamide-type triplet by a β-phenyl group in 1a while this interaction is less favorable in the most stable conformer of 1b (wherein the benzoyl moiety protrudes away from the cis phenyl groups).Steady-state photolysis and product analysis studies have provided evidence for photocleavage of both C-N and C-C bonds of the aziridine ring.
NON-CATALYTIC REDUCTION OF Α-OXIMINOKETONES AND Α-OXIMINOALCOHOLS TO ERYTHRO-2-AMINO-1-ARYLALKAN-1-OLS
Oppong-Boachie, Francis Kwabena
, p. 293 - 298 (2007/10/02)
A non-catalytic reduction of α-oximinoketones 1 and α-oximinoalcohols 2 to erythro-2-amino-1-arylalkan-1-ols 3 with lithium aluminium hydride is reported.The erythro-2-amino-1-arylalkan-1-ols are isolated as their hydrochlorides 5 and characterised as the erythro isomers by benzoylation.
