6619-09-6

Basic information

• Product Name: METHYL 6-O-TOSYL-ALPHA-D-GLUCOPYRANOSIDE
• Synonyms: METHYL 6-O-TOSYL-ALPHA-D-GLUCOPYRANOSIDE;methyl 6-O-((4-methylphenyl)sulfonyl)-alpha-D-galactopyranoside;Methyl 6-O-tosyl-alpha-D-galactopyranoside;Methyl 6-O-(4-methylphenyl)sulfonyl-α-D-glucopyranoside;Methyl 6-O-Tosyl-α-D-glucopyranoside;Methyl 6-O-tosyl-a-D-glucopyranoside
• CAS NO: 6619-09-6
• Molecular Formula: C₁₄H₂₀O₈S
• Molecular Weight: 348.37
• Mol File: 6619-09-6.mol

Chemical Properties

• Melting Point: 123-125 °C
• Boiling Point: 550.2°Cat760mmHg
• Flash Point: 286.5°C
• Appearance: /
• Density: 1.47g/cm³
• Vapor Pressure: 6.15E-13mmHg at 25°C
• Refractive Index: 1.597
• Storage Temp.: 2-8°C
• PKA: 12.81±0.70(Predicted)
• CAS DataBase Reference: METHYL 6-O-TOSYL-ALPHA-D-GLUCOPYRANOSIDE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 6-O-TOSYL-ALPHA-D-GLUCOPYRANOSIDE(6619-09-6)
• EPA Substance Registry System: METHYL 6-O-TOSYL-ALPHA-D-GLUCOPYRANOSIDE(6619-09-6)

Safety Data

• Hazardous Substances Data: 6619-09-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
METHYL 6-O-TOSYL-ALPHA-D-GLUCOPYRANOSIDE is used as an intermediate in the synthesis of Ranimustine (R120030), a nitrosourea alkylating agent approved in Japan for the treatment of chronic myelogenous leukemia and polycythemia vera.
Used in Biological Studies:
METHYL 6-O-TOSYL-ALPHA-D-GLUCOPYRANOSIDE is used as a research compound for studying the synthesis of anti-EGFR antibody-drug conjugates, which have potential applications in targeted cancer therapies.
Used in Therapeutic Applications:
METHYL 6-O-TOSYL-ALPHA-D-GLUCOPYRANOSIDE is used in the therapeutic use and biological study of BCMA (B-Cell Maturation Antigen) antigen binding proteins, which are being explored for their potential in treating certain types of cancer, particularly multiple myeloma.

InChI:InChI=1/C14H20O8S/c1-8-3-5-9(6-4-8)23(18,19)21-7-10-11(15)12(16)13(17)14(20-2)22-10/h3-6,10-17H,7H2,1-2H3

Upstream product

• 23661-33-8 methyl 2,3,4-tri-O-acetyl-6-O-(p-tolylsulfonyl)-α-D-glucopyranoside 
• 1153940-62-5 methyl-[O²,O³,O⁴-tribenzoyl-O⁶-(toluene-4-sulfonyl)-α-D-glucopyranoside] 
• 98-59-9 p-toluenesulfonyl chloride 
• 97-30-3 methyl-alpha-D-glucopyranoside 
• 23397-70-8 methyl 2,3-di-O-benzoyl-4,6-di-O-tosyl-α-D-glucopyranoside 
• 67-56-1 methanol 
• 7664-41-7 ammonia 
• 34234-44-1 methyl 2,3,4-tri-O-benzoylglucopyranoside 
• 20231-39-4 methyl 2,3,4-tri-O-benzoyl-6-O-triphenylmethyl-α-D-glucopyranoside 
• 7432-72-6 methyl 2,3,4-tri-O-acetyl-α-D-glucopyranose 
• 2232-08-8 N-tosylimidazole 

Downstream Products

• 180998-03-2 Toluene-4-sulfonic acid (2R,3R,4S,5R,6S)-6-methoxy-3,4,5-tris-trimethylsilanyloxy-tetrahydro-pyran-2-ylmethyl ester 
• 494804-64-7 C₁₄H₂₀O₅S 
• 1192817-52-9 C₇H₇O₃S^(1-)*C₁₂H₂₄NO₅⁽¹⁺⁾ 
• 1192817-45-0 C₇H₇O₃S^(1-)*C₁₁H₁₉N₂O₅⁽¹⁺⁾ 
• 942209-68-9 C₇H₇O₃S^(1-)*C₁₄H₂₃N₂O₅⁽¹⁺⁾ 
• 1192817-61-0 C₇H₇O₃S^(1-)*C₂₅H₅₀N₂O₅⁽²⁺⁾*Cl^(1-) 
• 1192817-67-6 C₇H₇O₃S^(1-)*C₂₉H₅₈N₂O₅⁽²⁺⁾*Cl^(1-) 
• 1192817-42-7 Br^(1-)*C₇H₇O₃S^(1-)*C₁₇H₃₄N₂O₅⁽²⁺⁾ 
• 1192817-55-2 C₇H₇O₃S^(1-)*C₂₀H₃₂N₂O₅⁽²⁺⁾*Cl^(1-) 
• 1192817-70-1 Br^(1-)*C₇H₇O₃S^(1-)*C₃₁H₆₂N₂O₅⁽²⁺⁾ 
• 1192817-64-3 Br^(1-)*C₇H₇O₃S^(1-)*C₂₇H₅₄N₂O₅⁽²⁺⁾ 
• 1192817-39-2 Br^(1-)*C₇H₇O₃S^(1-)*C₁₆H₃₂N₂O₅⁽²⁺⁾ 
• 1192817-48-3 Br^(1-)*C₇H₇O₃S^(1-)*C₁₇H₃₄N₂O₅⁽²⁺⁾ 
• 1192817-58-5 Br^(1-)*C₇H₇O₃S^(1-)*C₂₁H₄₂N₂O₅⁽²⁺⁾ 

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