66192-28-7

Upstream product

• 67-56-1 methanol 
• 66192-29-8 trans-2-bromo-4-methyl-cinnamic acid 
• 583-68-6 2-bromo-p-toluidine 
• 292638-85-8 acrylic acid methyl ester 
• 5927-18-4 trimethyl phosphonoacetate 
• 824-54-4 2-bromo-4-methylbenzaldehyde 

Downstream Products

• 615580-33-1 5-Methyl-2-[(S)-1-methyl-3-(tetrahydro-pyran-2-yloxy)-propyl]-phenol 
• 615580-31-9 5-Methyl-2-[(S)-1-methyl-3-(tetrahydro-pyran-2-yloxy)-propyl]-phenylamine 
• 615580-24-0 (S)-2-(4-(benzyloxy)butan-2-yl)-5-methylbenzenamine 
• 615580-26-2 1-((S)-3-Benzyloxy-1-methyl-propyl)-4-methyl-benzene 
• 615580-35-3 2-((S)-4-hydroxybutan-2-yl)-5-methylphenol 
• 70878-71-6 (S)-curcuphenol 
• 217301-15-0 (3S)-3-(2-Methoxy-4-methylphenyl)butan-2-ol 
• 3649-81-8 (S)-curcumene 
• 853685-28-6 (S)-3-(2-iodo-4-methylphenyl)butan-1-ol 
• 853685-27-5 (S)-trimethyl((5-methyl-2-(pent-4-en-2-yl)phenyl)ethynyl)silane 
• 615580-19-3 (S)-3-(2-Amino-4-methyl-phenyl)-butan-1-ol 
• 615580-15-9 ((2S,4S)-7-Methyl-2-oxo-2-phenyl-3,4-dihydro-2λ⁶-benzo[c][1,2]thiazin-4-yl)-acetic acid methyl ester 
• 615580-17-1 2-((2S,4S)-7-Methyl-2-oxo-2-phenyl-3,4-dihydro-2λ⁶-benzo[c][1,2]thiazin-4-yl)-ethanol 
• 853685-31-1 (S)-3-(4-methyl-2-((trimethylsilyl)ethynyl)phenyl)butan-1-ol 

Relevant academic research and scientific papers

Multicomponent, flow diazotization/mizoroki-heck coupling protocol: Dispelling myths about working with diazonium salts

A single pass flow diazotization/Mizoroki-Heck protocol has been developed for the production of cinnimoyl and styryl products. The factors that govern aryl diazonium salt stability have been examined in detail leading to the development of a MeOH/DMF co-solvent system in which the diazonium salts can be generated in the presence of all other reaction components and then coupled selectively to give the desired products. Finally the key role of the reaction quench for flow reactions has been demonstrated.

Benzothiazines in synthesis: Studies directed toward the synthesis of erogorgiaene

(Chemical Equation Presented) The use of benzothiazenes for the formal total synthesis of erogorgiaene and stereoselective total syntheses of two diastereomers of this natural product is described. In particular, the stereochemical course of a radical cyc

Benzothiazines in synthesis. Formal syntheses of (+)-curcumene and (+)-curcuphenol

A benzothiazine readily available in enantiomerically pure form via a stereoselective, intramolecular Michael addition reaction could be converted to a precursor to (+)-curcuphenol and to (+)-curcumene.

1,2,4,5-Tetrahydro-3H-2-benzazepin-3-ones

New physiologically active 1,2,4,5-tetrahydro-3H-2-benzazepin-3-ones having the general formula STR1 wherein R1 is hydrogen or phenyl, R2 is hydrogen, alkyl, C3 -C6 -alkenyl, C1 -C4 -acyl,