66236-09-7

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 87-62-7 2,6-dimethylaniline 
• 7143-01-3 Methanesulfonic anhydride 

Downstream Products

• 71381-44-7 N-Cyanomethyl-N-(2,6-dimethyl-phenyl)-methanesulfonamide 
• 71273-70-6 2-[(2,6-Dimethyl-phenyl)-methanesulfonyl-amino]-N,N-diethyl-acetamide 
• 71270-69-4 N-2-oxopropyl-2',6'-dimethyl-methanesulphonanilide 
• 71273-63-7 2-[(2,6-Dimethyl-phenyl)-methanesulfonyl-amino]-propionic acid 
• 71273-72-8 2-[(2,6-Dimethyl-phenyl)-methanesulfonyl-amino]-butyric acid 
• 83843-17-8 1-chloro-2--propane 
• 83843-14-5 1--2-propanol 
• 71270-12-7 N-[1-(2-(ethoxycarbonyl)hydrazinocarbonyl)ethyl]-2',6'-dimethylmethanesulphonanilide 
• 71270-11-6 {2-[(2,6-Dimethyl-phenyl)-methanesulfonyl-amino]-propionylamino}-acetic acid ethyl ester 
• 71269-98-2 2-[(2,6-Dimethyl-phenyl)-methanesulfonyl-amino]-propionic acid cyclohexyl ester 
• 71269-94-8 2-[(2,6-Dimethyl-phenyl)-methanesulfonyl-amino]-propionic acid isopropyl ester 
• 71270-50-3 N-[1-(hydrazinocarbonyl)ethyl]-2',6'-dimethylmethanesulphonanilide 
• 71273-68-2 2-[(2,6-Dimethyl-phenyl)-methanesulfonyl-amino]-propionamide 
• 71273-71-7 2-[(2,6-Dimethyl-phenyl)-methanesulfonyl-amino]-thioacetamide 

Relevant academic research and scientific papers

A Study of Steric and Electronic Effects in Some Methane- and Dimethane-sulphonanilides by 13C NMR Spectroscopy

The steric and electronic interactions in several methanesulphonanilides and dimethane-sulphonanilides have been examined on the basis of their 13C NMR chemical shifts.In aromatic amines there is evidence of nitrogen electron pair donation into the aromat

Palladium-catalyzed silane/siloxane reductions in the one-pot conversion of nitro compounds into their amines, hydroxylamines, amides, sulfonamides, and carbamates

A combination of palladium(II) acetate, aqueous potassium fluoride, and polymethylhydrosiloxane (PMHS) facilitates the room-temperature reduction of aromatic nitro compounds to anilines. These reactions tend to be quick (30 min), high-yielding, and tolerate a range of other functional groups. Replacement of PMHS/KF with triethylsilane allows for the reduction of aliphatic nitro compounds to their corresponding hydroxylamines. Depending on the substrate, both conditions can allow for the in situ conversion of the product amines into amides, sulfonamides, and carbamates. Georg Thieme Verlag Stuttgart.

Nitration and Bromination of N-(dimethylphenyl)methanesulfonamides

The orientation of the products of nitrosation: nitration and bromination of the methanesulfonamides of the six isomeric dimethylanilines have been established by 1H NMR nuclear Overhauser experiments.

A convenient reductive deamination (hydrodeamination) of aromatic amines

Reductive deamination (hydrodeamination) of aromatic amines can be conveniently carried out by amination of the corresponding arylamine methanesulfonamides using chloroamine under alkaline conditions. The intermediate aryl methanesulfonylhydrazines directly eliminate methanesulfinic acid, affording diazenes which extrude nitrogen affording the desired deaminated products. Both sulfonamide formation and reduction reactions occur in high yield and are compatible with a variety of functional groups.

Synthesis and aldose reductase inhibitory activities of novel N-nitromethylsulfonanilide derivatives

A novel series of 14 N-nitromethylsulfonanilide derivatives were synthesized and evaluated for their ability to inhibit recombinant aldose reductase. Computational docking simulations provided a good explanation for the observed structure-activity relatio

New alkylene diamine derivatives

The invention is directed to 1-(2,6-Dimethyl-Phenyl-amino)-2-Dimethyl-amino-Propane and the pharmaceutical composition thereof useful for the treatment of cardiac rhythm disorders.