66255-86-5Relevant academic research and scientific papers
Solvent-free preparation of α,α-dichloroketones with sulfuryl chloride
Tu, Dewei,Luo, Juan,Jiang, Wengao,Tang, Qiang
supporting information, (2021/09/15)
An efficient and facile method is reported for the synthesis of a series of α,α-dichloroketones. The direct dichlorination of methyl ketones and 1,3-dicarbonyls using an excess amount of sulfuryl chloride affords the corresponding gem-dichloro compounds in moderate to excellent yields. Moreover, the protocol features high yields, broad substrate scope, and simple reaction conditions without using any catalysts and solvents.
A Convenient Synthesis of 2,2-Dichloro-1-phenyl-1-alkanones and the Corresponding Imines
Kimpe, Norbert De,Coppens, Wim,Welch, John,Corte, Bart De
, p. 675 - 677 (2007/10/02)
N-(2,2-Dichloro-1-phenylalkylidene)isopropylamines were synthesized by deprotonation of N-(2,2-dichloro-1-phenylethylidene)isopropylamine by lithium diisopropylamide and reaction of the resulting 3,3-dichloro-1-azaallylic anion with alkyl bromides or iodi
