66336-69-4

Basic information

• Product Name: Oxiranecarbonitrile, 3-methyl-2-phenyl-
• CAS NO: 66336-69-4
• Molecular Formula: C10H9NO
• Molecular Weight: 159.188
• Mol File: 66336-69-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Oxiranecarbonitrile, 3-methyl-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Oxiranecarbonitrile, 3-methyl-2-phenyl-(66336-69-4)
• EPA Substance Registry System: Oxiranecarbonitrile, 3-methyl-2-phenyl-(66336-69-4)

Safety Data

• Hazardous Substances Data: 66336-69-4(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 143-33-9 sodium cyanide 
• 93-55-0 1-phenyl-propan-1-one 
• 773837-37-9 sodium cyanide 
• 2114-00-3 2-bromo-1-phenyl-1-propanone 

Downstream Products

• 4468-48-8 1-phenyl-1-cyanopropan-2-one 

Relevant articles and documents

BF3·OEt2-mediated [1,2]-aryl shift: Synthesis of functionalized α-arylnitriles via the bromination/cyanation/deformylation of substituted deoxybenzoin

A new sequential, tandem synthesis of functionalized α-arylnitriles via the bromination/cyanation/deformylation of substituted deoxybenzoin has developed. CuBr2-promoted bromination of substituted deoxybenzoins gives 2-bromo-2-arylacetophenne 3. The cyanation of 3 with sodium cyanide (NaCN) generates epoxynitrile. Then, a treatment of epoxynitrile with BF3·OEt2 results in the formation of functionalized α-arylnitriles 4 via a 1,2-aryl shift.