663603-70-1

Basic information

• Product Name: (2Z)-3-(METHYLAMINO)-1-(2-THIENYL)PROP-2-EN-1-ONE
• Synonyms: (2Z)-3-(METHYLAMINO)-1-(2-THIENYL)PROP-2-EN-1-ONE
• CAS NO: 663603-70-1
• Molecular Formula: C₈H₉NOS
• Molecular Weight: 167.23
• Mol File: 663603-70-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (2Z)-3-(METHYLAMINO)-1-(2-THIENYL)PROP-2-EN-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: (2Z)-3-(METHYLAMINO)-1-(2-THIENYL)PROP-2-EN-1-ONE(663603-70-1)
• EPA Substance Registry System: (2Z)-3-(METHYLAMINO)-1-(2-THIENYL)PROP-2-EN-1-ONE(663603-70-1)

Safety Data

• Hazardous Substances Data: 663603-70-1(Hazardous Substances Data)

Usage

General Description

The chemical compound (2Z)-3-(methylamino)-1-(2-thienyl)prop-2-en-1-one, also known as 2-methylamino-1-(2-thienyl)but-2-en-1-one, is a yellow to brown liquid with a strong odor. It belongs to the class of organic compounds known as thienylketones, which are compounds containing a ketone group substituted by a thienyl group. This chemical is used in the production of pharmaceuticals, pesticides, and other organic synthesis processes. It is also known for its potential use in the field of organic photovoltaics due to its semiconducting properties. However, it is important to handle this chemical with care as it may be hazardous if not properly handled or used.

Upstream product

• 593-51-1 methylamine hydrochloride 
• 34772-98-0 3-dimethylamino-1-thiophen-2-ylpropenone 
• 88-15-3 2-Acetylthiophene 
• 109-94-4 formic acid ethyl ester 
• 130371-57-2 βeta;-oxo-βeta;-(2-thienyl)propanal sodium salt 

Downstream Products

• 116539-57-2 (R)-3-(methylamino)-1-(thiophen-2-yl)propan-1-ol 
• 116539-56-1 3-(methylamino)-1-(thiophen-2-yl)propan-1-ol 

Relevant articles and documents

An efficient method for the synthesis of 2-pyridones: Via C-H bond functionalization

A simple and practical method to access N-substituted 2-pyridones via a formal [3+3] annulation of enaminones with acrylates based on RhIII-catalyzed C-H functionalization was developed. Control and deuterated experiments led to a plausible mechanism involving C-H bond cross-coupling and aminolysis cyclization. This strategy provides a short synthesis of structural motifs of N-substituted 2-pyridones.

(E)-N-MONOALKYL-3-OXO-3-(2-THIENYL)PROPENAMINE AND PROCESS FOR PRODUCING THE SAME AND (E,Z)-N-MONOALKYL-3-OXO-3-(2-THIENYL)PROPENAMINE AND PROCESS FOR PRODUCING THE SAME

It is intended to provide a process for producing (E)-N-monoalkyl-3-oxo-3-(2-thienyl)propenamine represented by the general formula (I): (wherein R represents an alkyl group having 1 to 4 carbon atoms), characterized by maintaining a solution in which (Z)-N-monoalkyl-3-oxo-3-(2-thienyl)propenamine is dissolved in a solvent at 25°C or lower thereby to deposit crystals and fractionating a crystal with a particle size of 100 μm or less from the deposited crystals; and a process for producing (E,Z)-N-monoalkyl-3-oxo-3-(2-thienyl)propenamine, characterized by adding a water-insoluble organic solvent to a reaction solution obtained by reacting an alkali metal salt of β-oxo-β-(2-thienyl) propanal with a monoalkylamine compound, adding a seed crystal containing (E)-N-monoalkyl-3-oxo-3-(2-thienyl)propenamine to an organic layer obtained by separation and maintaining the temperature at 25°C or lower.