66365-00-2Relevant academic research and scientific papers
Iron-catalyzed asymmetric epoxidation of β,β-disubstituted enones
Nishikawa, Yasuhiro,Yamamoto, Hisashi
, p. 8432 - 8435 (2011/07/29)
The combination of Fe(OTf)2 and novel phenanthroline ligands enables the catalytic asymmetric epoxidation of acyclic β,β- disubstituted enones, which have been a heretofore inaccessible substrate class. The reaction provides highly enantioenriched α,β-epoxyketones (up to 92% ee) that can be further converted to functionalized β-ketoaldehydes with an all-carbon quaternary center.
The Effect of Lewis Acid and Solvent on Concerted 1,2-Acyl Migration
Bach, Robert D.,Domagala, John M.
, p. 4181 - 4188 (2007/10/02)
Lewis acid catalyzed 1,2-benzoyl migration in (E)- and (Z)-1,3-diphenyl-2-buten-1-on oxides (dypnone oxides) is a concerted process that occurs with inversion of configuration at the migration terminus when nonpolar solvents are employed.In methanol solve
