6638-33-1

Upstream product

• 868-84-8 S,S-dimethyl dithiocarbonate 
• 5053-63-4 3-amino-1-phenylpropan-1-ol 
• 201230-82-2 carbon monoxide 
• 1256843-56-7 C₁₀H₁₁N₃O₂ 
• 34674-93-6 4-hydroxy-4-phenylbutanoic acid 
• 530-62-1 1,1'-carbonyldiimidazole 
• 51800-35-2 4-hydroxy-4-phenylbutyric acid hydrazide 

Downstream Products

• 94783-56-9 3-methyl-6-phenyltetrahydro-1,3-oxazin-2-one 
• 5053-63-4 3-amino-1-phenylpropan-1-ol 

Relevant academic research and scientific papers

Intramolecular conversion of N,N-bis(2-picolyl)ureas to cyclic carbamates

Herein, we present a new methodology for preparing 6-membered ring carbamates from a CuI-promoted cyclization of N,N-bis(2-picolyl)amine substituted ureas. The reactions work best in the presence of up to five-fold excess of CuCl at room temper

Novel synthetic route to fluoxetine

Racemic fluoxetine was synthesized from 3-benzoylpropionic acid in five steps in 54% overall yield. Copyright

Selective catalytic oxidative carbonylation of amino alcohols to ureas

Amino alcohols undergo W(CO)6-catalyzed oxidative carbonylation to the corresponding hydroxyalkylureas without protection of the hydroxyl group. Selected examples of 1,2-, 1,3-, 1,4-, and 1,5-amino alcohols were converted to the ureas in good to excellent yields, with only small amounts of the cyclic carbamates being formed. In contrast, the phosgene derivatives CDI and DMDTC undergo stoichiometric reactions with the amino alcohol substrates to afford ureas and cyclic carbamates with variable selectivity.