5053-63-4

Basic information

• Product Name: 3-AMINO-1-PHENYL-PROPAN-1-OL
• Synonyms: 3-AMINO-1-PHENYL-PROPAN-1-OL;AKOS BB-9499;RARECHEM AL BW 2289;3-Amino-1-phenyl-propan-1-ol ,98%;3-Amino-1-phenyl-propanol;1-Phenyl-1-hydroxy-3-aMinopropane;3-AMino-1-phenyl-1-propanol;3-Hydroxy-3-phenylpropylaMine
• CAS NO: 5053-63-4
• Molecular Formula: C₉H₁₃NO
• Molecular Weight: 151.21
• Product Categories: pharmacetical;Amines;Aromatics
• Mol File: 5053-63-4.mol
• Article Data: 31

Chemical Properties

• Melting Point: 50-53°C
• Boiling Point: 293 °C at 760 mmHg
• Flash Point: 131 °C
• Appearance: /
• Density: 1.074 g/cm³
• Vapor Pressure: 0.000809mmHg at 25°C
• Refractive Index: 1.56
• Storage Temp.: -20°C Freezer
• PKA: 14.13±0.20(Predicted)
• CAS DataBase Reference: 3-AMINO-1-PHENYL-PROPAN-1-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-1-PHENYL-PROPAN-1-OL(5053-63-4)
• EPA Substance Registry System: 3-AMINO-1-PHENYL-PROPAN-1-OL(5053-63-4)

Safety Data

• Hazard Codes: Xn
• Statements: 22-41
• Safety Statements: 26-39
• Hazardous Substances Data: 5053-63-4(Hazardous Substances Data)

Usage

Chemical Properties

Off-White to Pale Yellow Low Melting Solid

Uses

3-Phenyl-3-hydroxypropylamine (cas# 5053-63-4) is a compound useful in organic synthesis.

InChI:InChI=1/C9H13NO/c10-7-6-9(11)8-4-2-1-3-5-8/h1-5,9,11H,6-7,10H2

Upstream product

• 6638-33-1 6-phenyltetrahydro-1,3-oxazin-2-one 
• 614-16-4 Benzoylacetonitrile 
• 102470-69-9 bis-(6-phenyl-dihydro-[1,3]oxazin-3-yl)-methane 
• 1452423-40-3 3-[(diphenylmethyl)amino]-1-phenylpropan-1-ol 
• 937787-98-9 N-(ethoxycarbonyl)-3-amino-1-phenyl-1-propanol 
• 100-52-7 benzaldehyde 
• 75-05-8 acetonitrile 
• 100-42-5 styrene 
• 93-58-3 benzoic acid methyl ester 
• 98-86-2 acetophenone 
• 18776-12-0 3-chloro-1-phenyl-propan-1-ol 
• 936-59-4 3-chloropropiophenone 
• 75162-17-3 2-(2-hydroxy-2-phenylethyl)glycine 
• 99-73-0 para-bromophenacyl bromide 

Downstream Products

• 1250437-74-1 9,10-dihydro-N-(3-hydroxy-3-phenylpropyl)-9-oxoacridine-4-carboxamide 
• 109306-10-7 3-phenyl-3-(2-methylphenoxy) propylamine 
• 1250437-81-0 9,10-dihydro-9-oxo-N-(3-phenoxy-3-phenylpropyl)acridine-4-carboxamide 
• 1250437-79-6 9,10-dihydro-N-[3-(2-methylphenoxy)-3-phenylpropyl]-9-oxoacridine-4-carboxamide 
• 1250437-83-2 N-(3-chloro-3-phenylpropyl)-9,10-dihydro-9-oxoacridine-4-carboxamide 
• 745716-86-3 3-chloro-3-phenylpropylamine 
• 48166-95-6 3-phenyl-3-phenoxypropylamine 
• 34597-73-4 3-(Benzylamino)-1-phenyl-1-propanol 
• 1215021-58-1 3-benzyl-6-phenyl 1,2,3-oxathiazinane 2,2-dioxide 
• 244059-08-3 tert-butyl N-(3-hydroxy-3-phenylpropyl)-N-methylcarbamate 
• 1436389-46-6 ethyl (4-{3-[(tert-butoxycarbonyl)(methyl)amino]-1-phenylpropoxy}phenyl)(difluoro)acetate 
• 1436389-35-3 (4-{3-[(tert-butoxycarbonyl)(methyl)amino]-1-phenylpropoxy}phenyl)(difluoro)acetic acid 
• 651316-65-3 tert-butyl methyl{3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl}carbamate 
• 1436389-37-5 N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine trifluoroacetic acid 

Relevant articles and documents

Rapid Access to γ-Amino-α-aryl Alcohol Scaffolds via an Enamine-Based Heck Coupling

The γ-amino-α-aryl alcohol is a key functional group for the design of inhibitors directed toward a critical family of metabolic enzymes. Here we report the transformation of simple aryl halides to a highly functionalized benzyl (3-oxo-3-arylpropyl)carbamate intermediate that can rapidly be converted to a high value γ-amino-α-aryl alcohol. This chemistry is realized through a two-step process involving an enamine-based Heck coupling (EBHC) followed by a one-pot catalytic Cbz-deprotection and ketone reduction of EBHC products.

RAPIDLY RELEASED BIOORTHOGONAL CAGING GROUPS

Bioorthogonal molecules are disclosed and described. A bioorthogonal a molecule having a structure according to: Formula (I); where R2, R3, and R4 are independently selected from H, a substituted or unsubstituted C1/

HYDROXY ALIPHATIC SUBSTITUTED PHENYL AMINOALKYL ETHER DERIVATIVES

New hydroxy aliphatic substituted phenyl aminoalkyl ether compounds of formula (I), compositions thereof and their use as a medicament in the treatment of nervous system diseases and/or the treatment of developmental, behavioral and/or mental disorders associated with cognitive deficits.