6638-60-4

Usage

Uses

Used in Organic Synthesis:
2-Amino-7-bromofluorene is used as a key intermediate for the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and dyestuffs. Its unique structure allows for a wide range of chemical modifications, making it a valuable building block in the development of new molecules with desired properties.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Amino-7-bromofluorene is used as a starting material for the development of new drugs. Its chemical properties enable the creation of novel therapeutic agents with potential applications in treating various diseases and medical conditions.
Used in Agrochemical Industry:
2-Amino-7-bromofluorene is also utilized in the agrochemical sector as a precursor for the synthesis of pesticides and other crop protection agents. Its ability to form stable and effective compounds makes it a valuable component in the development of innovative agrochemical products.
Used in Dye Industry:
In the dye industry, 2-Amino-7-bromofluorene is employed as a raw material for the production of various dyes and pigments. Its chemical structure contributes to the color and stability of the resulting dyes, making it an important component in the formulation of high-quality colorants for various applications.

InChI:InChI=1/C13H10BrN/c14-10-1-3-12-8(6-10)5-9-7-11(15)2-4-13(9)12/h1-4,6-7H,5,15H2

Upstream product

• 6638-61-5 2-bromo-7-nitro-9H-fluorene 
• 153-78-6 2-aminofluorene 
• 1133-80-8 2-bromo-9H-fluorene 
• 607-57-8 2-nitro-9H-fluorene 
• 6942-36-5 methyl 2-bromo-5-nitrobenzoate 
• 332883-48-4 (2-bromo-5-nitro-phenyl)methanol 
• 6344-65-6 2,9-dibromo-7-nitro-fluorene 
• 7664-41-7 ammonia 

Downstream Products

• 740812-15-1 2-amino-7-bromo-9,9-bis(2-ethylhexyl)fluorene 
• 1785-40-6 3,7-dibromo-fluoren-2-ylamine 
• 1914-43-8 N-(3,7-dibromo-fluoren-2-yl)-acetamide 
• 16433-88-8 2,7-dibromofluorene 
• 854638-20-3 N-(3,7-dibromo-fluoren-2-yl)-toluene-4-sulfonamide 
• 1227420-98-5 (7-bromo-9,9-dibutyl-9H-fluoren-2-yl)-dibutylamine 
• 194673-64-8 (7-bromo-9H-fluoren-2-yl)-dibutyl amine 
• 1044746-50-0 2-amino-7-bromo-9,9-dibutylfluorene 
• 1227420-94-1 5-(7-dibutylamino-9H-fluoren-2-yl)-thiophene-2-carbaldehyde 
• 1294445-39-8 7-bromo-N-[(1-oxyl-4-bromo-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl]-9H-fluoren-2-amine radical 
• 1294445-38-7 7-bromo-N-[(1-oxyl-2,2,6,6-tetramethyl-1,2,3,6-tetrahydropyridine-4-yl)methyl]-9H-fluoren-2-amine radical 
• 1294445-37-6 7-bromo-N-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl]-9H-fluoren-2-amine radical 
• 1294445-42-3 7-bromo-N-methyl-N-[(2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl]-9H-fluoren-2-amine 
• 1294445-41-2 7-bromo-N-methyl-N-[(2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl]-9H-fluoren-2-amine radical 

Relevant academic research and scientific papers

Synthesis and studies on the photophysical/biophysical properties of triazolylfluorene-labeled 2′-deoxyuridines

The planar structure, attractive photophysical property, and scarcity of electronically conjugated fluorene-containing biomolecular building blocks have attracted recent research interest on synthesizing triazolylfluorene decorated nucleosides with modulated photophysical features. Herein, we report the synthesis of few fluorescent nucleosides wherein the C5 of 2′-deoxyuridine is electronically conjugated with fluorene analogues via Sonogashira cross-coupling and copper-catalyzed click reaction. The study of photophysical properties of the synthesized nucleosides shows that two of the synthesized nucleosides show interesting dual emission properties in various organic solvents. The dual emitting fluorene nucleosides might impact significantly in nucleic acid research for monitoring the DNA microenvironment. Furthermore, we evaluated the interaction of cyanofluorenyl 2′-deoxyuridine with Calf thymus DNA (ctDNA) and observed that this nucleoside could sense ctDNA via the generation of an enhanced fluorescence signal.

A N, N - diaryl - 2 - bromo - 6 - naphthylamine synthetic method and its application

The invention discloses a synthetic method of N, N-diaryl-2-bromine-6-naphthylamine. The synthetic method comprises the step of carrying out C-N coupled reaction on halogenated arene and a 6-bromine-2-naphthylamine unit to obtain an N, N-diaryl-2-bromine-6-naphthylamine unit. The invention also discloses application of N, N-diaryl-2-bromine-6-naphthylamine, namely, N, N-diaryl-2-bromine-6-naphthylamine provided by the invention is adopted as the raw material to prepare an organic semiconductor material; compared with the conventional synthetic method, the synthetic method of N, N-diaryl-2-bromine-6-naphthylamine provided by the invention is simple in synthetic route and high in comprehensive yield; the organic semiconductor material which contains a diaryl naphthyl amine functional unit and is prepared from N, N-diaryl-2-bromine-6-naphthylamine provided by the invention is relatively high in hole mobility and thin film morphology stability.

Synthesis and biological activities of aryl-ether-, biaryl-, and fluorene-aspartic acid and diaminopropionic acid analogs as potent inhibitors of the high-affinity glutamate transporter EAAT-2

Excitatory amino acid transporters (EAATs) play a pivotal role in maintaining glutamate homeostasis in the mammalian central nervous system, with the EAAT-2 subtype thought to be responsible for the bulk of the glutamate uptake in forebrain regions. A complete elucidation of the functional role of EAAT-2 has been hampered by the lack of potent and selective pharmacological tools. In this study, we describe the synthesis and biological activities of novel aryl-ether, biaryl-, and fluorene-aspartic acid and diaminopropionic acid analogs as potent inhibitors of EAAT-2. Compound (16) represents one of the most potent (IC50 = 85 ± 5 nM) and selective inhibitors of EAAT-2 identified to date.

Liquid crystal materials and devices

A novel liquid crystal material contains a compound having a molecular structure such that the material exhibits a liquid crystal phase, the molecular structure of the compound being SPC1 Or an orthosubstituted derivative thereof, where X and Y are different parasubstituents of the kind which promote liquid crystal behaviour, where the para substituent is a group selected from the following list; an alkyl group, an acyloxy group, an unsaturated group or an alkoxy group having more than one carbon atom; and where the para-substituent Y is a group selected from the following list; a cyano group, a nitro group, a group which includes a terminal cyano group, a group which includes a terminal nitro group and an acyloxy group. The material may be the said compound or it may be a multi-component solution or mixture containing it. The liquid crystal material may be nematic, smectic or cholesteric depending on the selection of the substituents X and Y. A device such as a twisted nematic effect device, incorporating the material may be operated at low temperatures. The material does not suffer from significant chemical and/or photochemical decomposition when used in a liquid crystal device.