6639-92-5

Basic information

• Product Name: Quinoxaline, 1-acetyl-1,2,3,4-tetrahydro- (9CI)
• Synonyms: Quinoxaline, 1-acetyl-1,2,3,4-tetrahydro- (9CI);1-ACETYL-1,2,3,4-TETRAHYDROQUINOXALINE;1-(3,4-DIHYDROQUINOXALIN-1(2H)-YL)ETHANONE
• CAS NO: 6639-92-5
• Molecular Formula: C10H12N2O
• Molecular Weight: 176.21508
• Product Categories: PIPERIDINE
• Mol File: 6639-92-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 406°C at 760 mmHg
• Flash Point: 199.4°C
• Appearance: /
• Density: 1.139g/cm³
• Vapor Pressure: 8.38E-07mmHg at 25°C
• Refractive Index: 1.559
• CAS DataBase Reference: Quinoxaline, 1-acetyl-1,2,3,4-tetrahydro- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Quinoxaline, 1-acetyl-1,2,3,4-tetrahydro- (9CI)(6639-92-5)
• EPA Substance Registry System: Quinoxaline, 1-acetyl-1,2,3,4-tetrahydro- (9CI)(6639-92-5)

Safety Data

• Hazardous Substances Data: 6639-92-5(Hazardous Substances Data)

Usage

General Description

Quinoxaline, 1-acetyl-1,2,3,4-tetrahydro- (9CI) is a chemical compound with the molecular formula C10H12N2O. It is a derivative of quinoxaline, which is a heterocyclic compound containing a benzene ring fused to a pyrazine ring. The 1-acetyl-1,2,3,4-tetrahydro- form of quinoxaline has a tetrahydroquinoline ring structure, with an acetyl group attached to the first carbon atom. This chemical compound is utilized in various pharmaceutical and industrial applications, including as an intermediate in the synthesis of organic compounds and in the research and development of potential drug candidates. It is important to handle this compound with care, as it may pose health and environmental hazards.

InChI:InChI=1/C10H12N2O/c1-8(13)12-7-6-11-9-4-2-3-5-10(9)12/h2-5,11H,6-7H2,1H3

Upstream product

• 3476-89-9 1,2,3,4-tetrahydroquinoxaline 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 
• 552-32-9 o-nitroacetanilide 
• 107616-24-0 N-(2-nitrophenyl)-N-(2-propenyl)acetamide 

Downstream Products

• 2427-93-2 1-(4-benzyl-3,4-dihydroquinoxalin-1(2H)-yl)ethanone 
• 7092-76-4 benzo-1,5-diazabicyclo<3.2.2>nonene 

Relevant articles and documents

SHP2 PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF

The present disclosure relates to novel compounds including formula (X) and pharmaceutical compositions thereof, and methods for inhibiting the activity of SHP2 phosphatase with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders associated with SHP2 deregulation with the compounds and compositions of the disclosure.

COMPOUND HAVING 11 ?-HSD1 INHIBITORY ACTIVITY

The present invention provides compounds having excellent 11β-HSD1 inhibitory activity. A compound represented by the following formula (I): [wherein X1 represents an oxygen atom, or the formula -(CR11R12)p-, etc., Y1 represents a hydrogen atom, a hydroxyl group, etc., Z1 represents an oxygen atom or the formula -(NR14)-, R1 represents a hydrogen atom, a halogen atom, a cyano group, a C1-4 alkyl group, a C1-4 alkyl group substituted with 1 to 3 halogen atoms, a C1-4 alkoxy group, a C1-4 alkoxycarbonyl group, a carboxyl group, a carbamoyl group, or an amino group, and m represents an integer of 1 or 2, and R2 represents a hydrogen atom or a C1-4 alkyl group, and n represents an integer of 1 or 2].

Substituted pyridoquinoxaline-6-carboxylic acids and derivatives thereof

Antimicrobial compounds having the heterocyclic nucleus pyrido[1,2,3-de]quinoxaline are disclosed. The process of making the compounds and novel intermediates are also disclosed.