6647-76-3

Basic information

• Product Name: 1-[(4-bromophenyl)sulfonyl]triaza-1,2-dien-2-ium
• CAS NO: 6647-76-3
• Molecular Formula: C₆H₄BrN₃O₂S
• Molecular Weight: 263.0913
• Mol File: 6647-76-3.mol
• Article Data: 33

Chemical Properties

• CAS DataBase Reference: 1-[(4-bromophenyl)sulfonyl]triaza-1,2-dien-2-ium(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(4-bromophenyl)sulfonyl]triaza-1,2-dien-2-ium(6647-76-3)
• EPA Substance Registry System: 1-[(4-bromophenyl)sulfonyl]triaza-1,2-dien-2-ium(6647-76-3)

Safety Data

• Hazardous Substances Data: 6647-76-3(Hazardous Substances Data)

Usage

Explanation

Different sources of media describe the Explanation of 6647-76-3 differently. You can refer to the following data:
1. The molecular formula represents the number of atoms of each element present in a molecule of the compound.
2. The IUPAC name is a systematic method of naming chemical compounds, providing a unique name for each substance.
3. The common name is a more informal and widely recognized name for the compound, often used in the scientific community.
4. The compound belongs to the tosylamide family of chemicals, which are known for their use in organic synthesis and pharmaceutical intermediates.
5. These functional groups are the key structural features of the compound, which contribute to its chemical properties and reactivity.
6. The compound is widely used in the synthesis of various organic compounds and serves as a building block for pharmaceutical intermediates.
7. As a reagent in organic chemistry, the compound is commonly used to facilitate the formation of these important types of chemical bonds.
8. The compound has been investigated for its potential use in the development of new drugs and the creation of compounds with biological activity.

Family

Tosylamide

Functional groups

Triaza-1,2-diene, sulfonyl group, 4-bromophenyl substituent

Application

Organic synthesis, pharmaceutical intermediates

Reactivity

Formation of carbon-carbon and carbon-nitrogen bonds

Potential applications

Medicinal chemistry, synthesis of biologically active compounds

Upstream product

• 701-34-8 4-bromo-benzenesulfonic acid amide 
• 2297-64-5 p-bromophenylsulfonyl hydrazide 
• 138-36-3 p-bromobenzene sulfonic acid 
• 498-83-9 4-bromobenzenesulfonyl fluoride 
• 98-58-8 4-bromobenzenesulfonyl chloride 

Downstream Products

• 135885-64-2 4-Bromo-N-[1-(1,2,3,4,5,6-hexahydro-pentalen-2-yl)-1-methoxy-meth-(Z)-ylidene]-benzenesulfonamide 
• 83681-05-4 N-<(p-bromophenyl)sulfonyl>-2-methylcyclopentanecarboxamide 
• 83681-07-6 N-<(p-bromophenyl)sulfonyl>-1-methylcyclopentanecarboxamide 
• 135928-50-6 4-Bromo-N-[2,10-dimethyl-7-oxa-spiro[4.5]dec-2-en-(6Z)-ylidene]-benzenesulfonamide 
• 135885-71-1 4-Bromo-N-((4S,4aS,8aR)-8a-methoxy-4,7-dimethyl-3,4,8,8a-tetrahydro-2H,5H-chromen-4a-yl)-benzenesulfonamide 
• 135885-71-1 4-Bromo-N-((4R,4aS,8aR)-8a-methoxy-4,7-dimethyl-3,4,8,8a-tetrahydro-2H,5H-chromen-4a-yl)-benzenesulfonamide 
• 135885-67-5 4-Bromo-N-[1-[4-(2-hydroxy-ethyl)-1,2,3,4,5,6-hexahydro-pentalen-2-yl]-1-methoxy-meth-(Z)-ylidene]-benzenesulfonamide 
• 135885-69-7 Acetic acid 3-(1-{[(Z)-4-bromo-benzenesulfonylimino]-methoxy-methyl}-3-methyl-cyclopent-3-enyl)-butyl ester 
• 135885-65-3 Acetic acid 2-(5-{[(Z)-4-bromo-benzenesulfonylimino]-methoxy-methyl}-1,2,3,4,5,6-hexahydro-pentalen-1-yl)-ethyl ester 
• 108186-00-1 4-Bromo-N-[1-((1R,2R)-1,2-dimethyl-cyclopent-3-enyl)-1-methoxy-meth-(Z)-ylidene]-benzenesulfonamide 
• 108186-02-3 4-Bromo-N-[1-((1R,2S)-2,3-dimethyl-cyclopent-3-enyl)-1-methoxy-meth-(Z)-ylidene]-benzenesulfonamide 
• 108185-97-3 4-Bromo-N-[1-methoxy-1-(3-methoxy-1-methyl-cyclopent-3-enyl)-meth-(Z)-ylidene]-benzenesulfonamide 
• 83681-08-7 N-<(p-bromophenyl)sulfonyl>-1,2-dimethylcyclopentanecarboxamide 
• 83681-06-5 N-<(p-bromophenyl)sulfonyl>-2,4-dimethylcyclopentanecarboxamide 

Relevant articles and documents

Nickel-mediated C(sp2)-H amidation in synthesis of secondary sulfonamides via sulfonyl azides as amino source

In this paper, Ni(II)- Catalyzed ortho-amidation of C(sp2)-H bond with sulfonyl azides directed by (quinolin-8-yl) amine (AQ-amine) is described. The method provides a straightforward method for the synthesis of sulfonamides from available sulfonyl azides via the transition-metal-catalyzed C(sp2)-N bond forming reaction. The amidation reactions exhibit high functional group compatibility, which might proceed a Ni(III)/Ni(I) catalytic cycle. We also applied sulfonamide compound in OLEDs, which exhibits the certain application potential in OLEDs field.

One-pot synthesis of sulfonyl-1H-1,2,3-triazolyl-thiomorpholine 1,1-dioxide derivatives and evaluation of their biological activity

A one-pot procedure for the synthesis of novel 1,2,3-triazole derivatives (5a–5l) in good yields (63 to 77%) using different sulfonic acids and 4-(prop-2-yn-1-yl)thiomorpholine 1,1-dioxide through the in situ generated sulfonyl azides was developed. The structures of the newly synthesized compounds were confirmed by 1H NMR, 13C NMR, mass spectrometry, and elemental analysis. The newly synthesized compounds were screened for in?vitro antibacterial activity and free radical scavenging activity in terms of hydrogen donating or radical scavenging ability by the DPPH method. Among all, the compound N-(4-((4-((1,1-dioxidothiomorpholino) methyl)-1H-1,2,3-triazol-1-yl)sulfonyl)phenyl) acetamide (5l) was found to exhibit potent activity as compared to the standard drugs.

Pd-catalyzed amidation of 1,3-diketones with CO and azidesviaa nitrene intermediate

An efficient Pd-catalyzed amidation of 1,3-diketones has been developed using carbon monoxide and organic azides. This reaction provides a step-economic approach to produce β-ketoamides from readily available compounds under mild ligand-, oxidant-, and base-free conditions. The mechanistic studies showed that the reaction occurred through anin situgenerated isocyanate intermediate.