66496-58-0

Basic information

• Product Name: 3-[(2,6-dichlorobenzyl)oxy]-2-nitropyridine
• Synonyms: 3-[(2,6-dichlorobenzyl)oxy]-2-nitropyridine
• CAS NO: 66496-58-0
• Molecular Formula: C₁₂H₈Cl₂N₂O₃
• Molecular Weight: 299.10952
• Mol File: 66496-58-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-[(2,6-dichlorobenzyl)oxy]-2-nitropyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[(2,6-dichlorobenzyl)oxy]-2-nitropyridine(66496-58-0)
• EPA Substance Registry System: 3-[(2,6-dichlorobenzyl)oxy]-2-nitropyridine(66496-58-0)

Safety Data

• Hazardous Substances Data: 66496-58-0(Hazardous Substances Data)

Upstream product

• 83-38-5 2,6-dichlorobenzaldehyde 
• 15128-82-2 3-hydroxy-2-nitropyridine 
• 15258-73-8 2,6-dichlorobenzyl alcohol 
• 13505-06-1 4-nitro-pyridin-3-ol 
• 20443-98-5 2,6-Dichlorobenzyl bromide 

Downstream Products

• 756503-57-8 3-(2,6-dichlorobenzyloxy)-5-bromopyridin-2-amine 
• 107229-64-1 2-Amino-3-(2,6-dichlorobenzyloxy)pyridine 

Relevant articles and documents

Spiro compounds, preparation method thereof, intermediate, pharmaceutical composition and application

The invention discloses a spiro compound as shown in a formula I, a pharmaceutically acceptable salt, a hydrate, a solvate, an optical isomer or a prodrug of the spiro compound, as well as a preparation method, an intermediate, a pharmaceutical composition and an application of the spiro compound. The spiro compound disclosed by the invention has the activity of serving as protein kinase inhibitors and tyrosine kinase inhibitors such as c-Met, and the spiro compound can be used for treating diseases caused by the abnormal activity of kinases, such as cancer, or used for preparing medicaments for treating the diseases.