66504-69-6

Upstream product

• 66503-91-1 1-phenyl-3-azabicyclo<3.1.0>hexane-2,4-dione 
• 93579-36-3 1-(p-nitrophenyl)-cyclopropane-1,2-dicarboxylic acid 
• 4691-72-9 ethyl α-bromo-p-nitrophenylacetate 
• 63162-65-2 1-phenylcyclopropanedicarboxylic acid 

Downstream Products

• 93579-70-5 3-isopropyl-1-(4-nitrophenyl)-3-azabicyclo[3.1.0]hexane-2,4-dione 
• 93579-72-7 3-n-butyl-1-(4-nitrophenyl)-3-azabicyclo[3.1.0]hexane-2,4-dione 
• 93579-78-3 3-(2,2-Dimethyl-propyl)-1-(4-nitro-phenyl)-3-aza-bicyclo[3.1.0]hexane-2,4-dione 
• 93579-74-9 3-isobutyl-1-(4-nitrophenyl)-3-azabicyclo[3.1.0]hexane-2,4-dione 
• 93579-76-1 1-(4-nitrophenyl)-3-n-pentyl-3-azabicyclo[3.1.0]hexane-2,4-dione 
• 86215-68-1 1-(4-aminophenyl)-3-azabicyclo[3.1.0]hexane-2,4-dione 
• 93579-34-1 3-benzyl-1-(4-nitrophenyl)-3-azabicyclo[3.1.0]hexane-2,4-dione 
• 93579-67-0 3-ethyl-1-(4-nitrophenyl)-3-azabicyclo[3.1.0.]hexane-2,4-dione 
• 93579-69-2 1-(4-Nitro-phenyl)-3-propyl-3-aza-bicyclo[3.1.0]hexane-2,4-dione 
• 93610-02-7 1-(4-nitrophenyl)-3-propargyl-3-azabicyclo[3.1.0]hexane-2,4-dione 
• 93579-65-8 3-methyl-1-(4-nitrophenyl)-3-azabicyclo[3.1.0]hexane-2,4-dione 
• 93579-75-0 1-(4-Aminophenyl)-3-n-pentyl-3-azabicyclo[3.1.0]hexane-2,4-dione 
• 93579-43-2 1-<4-(methylamino)phenyl>-3-azabicyclo<3.1.0>hexane-2,4-dione 
• 93579-64-7 1-(4-Aminophenyl)-3-methyl-3-azabicyclo[3.1.0]hexane-2,4-dione 

Relevant academic research and scientific papers

C3-CARBON LINKED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION

This invention provides Degronimers that have carbon-linked E3 Ubiquitin Ligase targeting moieties (Degrons), which can be linked to a targeting ligand for a protein that has been selected for in vivo degradation, and methods of use and compositions thereof as well as methods for their preparation.