93579-39-6

Upstream product

• 4691-72-9 ethyl α-bromo-p-nitrophenylacetate 
• 86215-68-1 1-(4-aminophenyl)-3-azabicyclo[3.1.0]hexane-2,4-dione 
• 75-36-5 acetyl chloride 
• 926-63-6 N,N-dimethylaminopropane 
• 63162-65-2 1-phenylcyclopropanedicarboxylic acid 
• 66504-69-6 1-(4-nitrophenyl)-3-azabicyclo<3.1.0>hexane-2,4-dione 
• 66503-91-1 1-phenyl-3-azabicyclo<3.1.0>hexane-2,4-dione 
• 108-24-7 acetic anhydride 

Downstream Products

• 93579-48-7 1-(4-Aminophenyl)-3-allyl-3-azabicyclo[3.1.0]hexane-2,4-dione 
• 93579-47-6 1-<4-(acetylamino)phenyl>-3-allyl-3-azabicyclo<3.1.0>hexane-2,4-dione 

Relevant academic research and scientific papers

C3-CARBON LINKED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION

This invention provides Degronimers that have carbon-linked E3 Ubiquitin Ligase targeting moieties (Degrons), which can be linked to a targeting ligand for a protein that has been selected for in vivo degradation, and methods of use and compositions thereof as well as methods for their preparation.

Substituted azabicycloalkanes, the use thereof, pharmaceutical compositions containing them

1-Phenyl-3-azabicyclo[3.1.0]hexane-2,4-diones of the formula STR1 wherein R1 is hydrogen, R2 is hydrogen, sulfo or acyl and R3 is hydrogen, or R1 is a saturated or unsaturated aliphatic, cycloaliphatic or cycloa