66546-90-5 Usage
General Description
Ethyl 2-cyano-2-propylvalerate, also known as ethyl valproate, is a chemical compound with the molecular formula C9H15NO2. It is classified as an ester, and it is widely used as an antiepileptic medication to treat seizures. Ethyl 2-cyano-2-propylvalerate works by increasing the levels of a neurotransmitter called gamma-aminobutyric acid (GABA) in the brain, which helps to control electrical activity and decrease seizure activity. It is also being studied for its potential therapeutic applications in mood disorders and as an anti-inflammatory agent. However, it is important to note that ethyl 2-cyano-2-propylvalerate has potential side effects and should only be used under the supervision of a healthcare professional.
Check Digit Verification of cas no
The CAS Registry Mumber 66546-90-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,5,4 and 6 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 66546-90:
(7*6)+(6*6)+(5*5)+(4*4)+(3*6)+(2*9)+(1*0)=155
155 % 10 = 5
So 66546-90-5 is a valid CAS Registry Number.
InChI:InChI=1/C11H19NO2/c1-4-7-11(9-12,8-5-2)10(13)14-6-3/h4-8H2,1-3H3
66546-90-5Relevant articles and documents
Synthesis of new N-glycosides based on Valproic acid analogs tetrazole derivatives
Noroozi Pesyan, Nader,Ebrahimi, Marziyeh
, p. 1059 - 1067 (2017/03/11)
New N-glycosides based on valproic acid analogs tetrazole derivatives were synthesized. The bis-tetrazole derived from 1,6-hexandiol was also connected to acetylated glucose and formed bis-N-glycoside. Structures characterizations have been performed using FT IR, 1H and 13C NMR spectroscopy.
Synthesis and biological evaluation of cryptophycin analogs with substitution at C-6 (fragment C region)
Varie, David L.,Shih, Chuan,Hay, David A,Andis, Sherri L.,Corbett, Tom H.,Gossett, Lynn S.,Janisse, Samantha K.,Martinelli, Michael J.,Moher, Eric D.,Schultz, Richard M.,Toth, John E.
, p. 369 - 374 (2007/10/03)
Analogs of the antitumor agents cryptophycins 1 and 8 with dialkyl substitution at C-6 (fragment C) were synthesized and evaluated for in vitro cytotoxicity against human leukemia cells (CCRF-CEM). The activity of these analogs decreased as the size of the substituents at C-6 increased. The C-6 spirocylopropyl compound (2g) was highly potent in vitro and showed excellent antitumor activity in animal models.