66560-21-2

Upstream product

• 66502-25-8 propoxyacetonitrile 
• 98-88-4 benzoyl chloride 
• 71-23-8 propan-1-ol 
• 3282-32-4 2-diazo-acetophenone 
• 108-86-1 bromobenzene 

Downstream Products

• 128173-66-0 3-Cyano-6-(2-propoxyphenyl)-2(1H)-pyridinethione 
• 137040-13-2 2-Hydroxy-2-phenyl-3-propoxy-propionic acid 1-aza-bicyclo[2.2.2]oct-3-yl ester 
• 137040-06-3 2-Hydroxy-2-phenyl-3-propoxy-propionic acid ethyl ester 
• 137039-92-0 2-Hydroxy-2-phenyl-3-propoxy-propionamide 
• 137039-99-7 2-Hydroxy-2-phenyl-3-propoxy-propionic acid 
• 79598-12-2 2-Brom-1,3-diphenyl-2-propoxy-propan-1,3-dion 
• 79598-00-8 1,3-Diphenyl-2-propoxy-propan-1,3-dion 
• 79597-89-0 1-Hydroxy-1,3-diphenyl-2-propoxy-1-propen-2-on 
• 137039-85-1 2-Phenyl-3-propoxy-2-trimethylsilanyloxy-propionitrile 

Relevant academic research and scientific papers

Indium triflate: A mild and efficient Lewis acid catalyst for O-H insertion reactions of α-diazo ketones

Facile O-H insertion reactions of α-diazo ketones with aliphatic/aromatic alcohols or benzenethiol have been developed in the presence of indium triflate as a catalyst. These reactions provided good yields of α-alkoxy ketones. A comparative study with other Lewis acids establishes the reactivity of indium triflate in O-H insertion reactions of α-diazo ketones.

A new and mild heterogeneous catalytic decomposition of α-diazo carbonyl compounds using montmorillonite or zeolite

A very mild method of decomposition of various α-diazo carbonyl compounds 1 in the presence of environmentally attractive solid acids such as montmorillonite K-10 or zeolite H-Y in a heterogeneous manner to furnish α-hydroxy/alkoxy ketones in very good yield is reported. Interestingly, novel bicycloalkane-1,3-diones and 3-furanones were obtained as unusual products in the case of aliphatic/alicyclic α-diazo carbonyl compounds.

Synthesis and Muscarinic Cholinergic Receptor Affinities of 3-Quinuclidinyl α-(Alkoxyalkyl)-α-aryl-α-hydroxyacetates

Seven analogues of 3-quinuclidinyl benzilate (QNB) in which one phenyl ring was replaced by an alkoxyalkyl moiety were synthesized and their affinities for the muscarinic cholinergic receptor determined.An oxygen in the β-position of the moienty was not w

Stable Enols of α-dibenzoylmethanes

The enols 13a-m of α-(aryloxy)- and α-(alkyloxy)dibenzoylmethanes 4a-m are obtained by decomposition of the copper chelates 11a-m with sulfuric acid.The copper compounds are synthesized either by ester condensation of the acetophenones 6h-m with phenyl benzoate (7) or by nucleophilic substitution of α-bromodibenzoylmethane (9) with the phenols 10a-g.The enolates 8, primarily formed in the presence of sodium hydride or triethylamine, respectively, are directly converted into the chelates 11 with copper(II) acetate.The enols 13 are characterized by isomerization to the β-diketones 4 as well as by bromination to 12.

Hydantoin derivatives as potential antiinflammatory agents

The hydantoins 2a-c and three hydantoic acids were synthesized and their anti-inflammatory properties were determined in the rat paw oedema test. Neither 1-phenyl-sulphonyl-5,5-diphenylhydantoin, which has been described as an inflammatory, nor any of the other compounds, showed significant anti-inflammatory activity.