66602-64-0

Upstream product

• 350-46-9 4-Fluoronitrobenzene 
• 79-04-9 chloroacetyl chloride 
• 70441-63-3 4-fluoro-N-isopropyl-aniline 

Downstream Products

• 64212-66-4 O,O-Diethyl S-(N-isopropyl-4-fluorophenylcarbamoylmethyl)dithiophosphate 
• 64212-68-6 Dithiophosphoric acid S-{[(4-fluoro-phenyl)-isopropyl-carbamoyl]-methyl} ester O,O'-diisopropyl ester 
• 64212-69-7 Dithiophosphoric acid S-{[(4-fluoro-phenyl)-isopropyl-carbamoyl]-methyl} ester O,O'-dipropyl ester 
• 54041-17-7 N-(4-fluorophenyl)-2-hydroxy-N-(1-methylethyl)acetamide 
• 812659-62-4 2-(benzo[d]thiazol-2-yloxy)-N-(4-fluorophenyl)-N-isopropylacetamide 
• 142459-58-3 flufenacet 
• 64212-70-0 Dithiophosphoric acid O,O'-dibutyl ester S-{[(4-fluoro-phenyl)-isopropyl-carbamoyl]-methyl} ester 
• 64213-58-7 Isobutyl-phosphonodithioic acid S-{[(4-fluoro-phenyl)-isopropyl-carbamoyl]-methyl} ester O-isobutyl ester 
• 64214-05-7 Dimethyl-thiophosphoramidic acid O-ethyl ester S-{[(4-fluoro-phenyl)-isopropyl-carbamoyl]-methyl} ester 
• 64213-59-8 Methyl-phosphonothioic acid S-{[(4-fluoro-phenyl)-isopropyl-carbamoyl]-methyl} ester O-isobutyl ester 
• 64213-57-6 Methyl-phosphonodithioic acid S-{[(4-fluoro-phenyl)-isopropyl-carbamoyl]-methyl} ester O-isobutyl ester 
• 64213-56-5 Ethyl-phosphonodithioic acid O-ethyl ester S-{[(4-fluoro-phenyl)-isopropyl-carbamoyl]-methyl} ester 
• 64213-55-4 Methyl-phosphonodithioic acid O-ethyl ester S-{[(4-fluoro-phenyl)-isopropyl-carbamoyl]-methyl} ester 
• 64249-07-6 Methyl-phosphonodithioic acid S-{[(4-fluoro-phenyl)-isopropyl-carbamoyl]-methyl} ester O-methyl ester 

Relevant academic research and scientific papers

Synthetic method N - (4 - fluoroaniline) -2 - hydroxyl - N - isopropyl acetamide

The invention belongs to the technical field of medical intermediates, and particularly relates to a synthesis method N - (4 - fluoroaniline) -2 - hydroxyl - N - isopropylacetamide. To the invention, fluoronitrobenzene is used as a starting material, and hydrogenation is carried out. Condensation gives compound A, compound A is coupled to compound B by amide coupling, compound B is subjected to nucleophilic substitution reaction to give compound C, compound C is exchanged through ester exchange to obtain N - (4 - fluoroaniline) -2 - hydroxyl - N - isopropyl acetamide. The synthesis route of the complete N - (4 - fluoroaniline) -2 - hydroxyl - N - isopropyl acetamide is provided, and the synthesized N - (4 - fluoroaniline) -2 - hydroxyl - N - isopropyl acetamide is high in yield and high in purity.

Flufenacet preparation method

The invention discloses a flufenacet preparation method, which comprises synthesis of 2-methylsulfonyl-5-trifluoromethyl-1,3,4-thiadiazole, synthesis of 2-hydroxy-N-(4-fluoroaniline)-N-(1-methylethyl)acetamide and synthesis of 4'-fluoro-N-isopropyl-2-[5-(trifluridine)-1,3,4-thiadiazole-2-imide]acetamide. The optimal flufenacet preparation method is screened by a large number of experiments, the whole process is reasonable in design, particularly the steps of screening optimal reaction conditions and the optimal amount ratio, reaction temperature, reaction time and the like of reaction raw materials, the reaction yield (capable of reaching 90 percent or more) can be greatly increased, side reaction can be reduced, the reaction rate can be increased, the reaction raw materials can be recycled, the production cost is greatly reduced, and a broad application prospect is achieved.

A 2-chloro-N-(4-fluoro phenyl)-N-isopropyl acetamide method for the preparation of

The invention discloses a method for preparing 2-chloro-N-(4-fluorophenyl)-N-isopropylacetamide. The method comprises the steps as follows: N-isopropyl-4-fluoroaniline and chloroacetyl chloride are taken as raw materials, triethylamine is taken as an acid

Process for the preparation of glycoloylanilides

A process for the preparation of glycoloylanilide of the formula (G) STR1 is recited that involves reacting a nitrobenzene with hydrogen and, if desired, with a carbonyl compound, in the presence of a noble metal catalyst and a solvent, reacting the compound produced with chloroacetyl chloride, reacting the resulting product with a benzyl alcohol and with a base, or reacting the resulting compound with an O-benzylglycoloyl chloride, and debenzylating the resulting benzylglycoloylanilide product by reacting with hydrogen in the presence of a noble metal catalyst. The invention also relates to a process for the preparation of O-benzylglycoloylanilide.

N-Isopropylcarbanilylmethyl dithiophosphates

A class of compounds having the structural formula STR1 in which Ar is substituted phenyl and R is methyl or ethyl possesses improved activity as pre-emergent herbicides and insecticides.