6665-74-3

Basic information

• Product Name: GALANGIN-3-METHYLETHER
• Synonyms: GALANGIN-3-METHYLETHER;3-Methoxy-2-phenyl-5,7-dihydroxy-4H-1-benzopyran-4-one;3-O-Methylgalangin;5,7-Dihydroxy-3-methoxyflavone;Galangin 3-O-methyl ether;3-methylgalangin
• CAS NO: 6665-74-3
• Molecular Formula: C₁₆H₁₂O₅
• Molecular Weight: 284.26
• Mol File: 6665-74-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 299 °C
• Boiling Point: 526.4°C at 760 mmHg
• Flash Point: 201.5°C
• Appearance: /
• Density: 1.47g/cm³
• Vapor Pressure: 1.06E-11mmHg at 25°C
• Refractive Index: 1.692
• PKA: 6.32±0.40(Predicted)
• CAS DataBase Reference: GALANGIN-3-METHYLETHER(CAS DataBase Reference)
• NIST Chemistry Reference: GALANGIN-3-METHYLETHER(6665-74-3)
• EPA Substance Registry System: GALANGIN-3-METHYLETHER(6665-74-3)

Safety Data

• Hazardous Substances Data: 6665-74-3(Hazardous Substances Data)

Usage

Definition

ChEBI: A monomethoxyflavone that is galangin in which the hydroxy group at position 3 has been replaced by a methoxy group.

InChI:InChI=1/C16H12O5/c1-20-16-14(19)13-11(18)7-10(17)8-12(13)21-15(16)9-5-3-2-4-6-9/h2-8,17-18H,1H3

Upstream product

• 55317-02-7 2-methoxy-1-(2,4,6-trihydroxyphenyl)ethanone 
• 93-97-0 benzoic acid anhydride 
• 69789-10-2 3,4-bis(benzoyloxy)benzoic acid 
• 17892-78-3 5-hydroxy-3-methoxy-7-tosyloxyflavone 
• 548-83-4 galangin 
• 77-78-1 dimethyl sulfate 
• 99-50-3 3,4-Dihydroxybenzoic acid 
• 854693-27-9 3,4-bis-benzoyloxy-benzoic acid-anhydride 

Downstream Products

• 33803-39-3 5,7,8-triacetoxy-3-methoxy-2-phenyl-chromen-4-one 
• 710338-05-9 7-benzyloxy-3,5-dimethoxy-2-phenyl-chromen-4-one 
• 94306-14-6 7-acetoxy-3,5-dimethoxy-2-phenyl-chromen-4-one 
• 155801-47-1 7-ethoxy-3,5-dimethoxy-2-phenyl-chromen-4-one 
• 480-14-8 isalpinin 
• 39869-03-9 7-hydroxy-3,5-dimethoxyflavone 
• 78433-52-0 3,5-dimethoxy-2-phenyl-chromen-4-one 
• 727381-93-3 5-hydroxy-3-methoxy-2-phenyl-chromen-4-one 
• 98498-25-0 Acetic acid 6,8-dibenzhydryl-5-hydroxy-3-methoxy-4-oxo-2-phenyl-4H-chromen-7-yl ester 
• 98498-30-7 3,5,7-trimethoxy-6,8-bis(diphenylmethyl)flavone 
• 98498-29-4 5-hydroxy-3,7-dimethoxy-6,8-bis(diphenylmethyl)flavone 
• 98498-28-3 Acetic acid 7-acetoxy-6-benzhydryl-3-methoxy-4-oxo-2-phenyl-4H-chromen-5-yl ester 
• 98498-26-1 Acetic acid 5-acetoxy-8-benzhydryl-3-methoxy-4-oxo-2-phenyl-4H-chromen-7-yl ester 
• 98498-32-9 3,5,7-trimethoxy-6-(diphenylmethyl)flavone 

Relevant articles and documents

Synthesis of some commonly occurring 2-phenyl-4H-1-benzopyran-4-ones: Revised structures for three natural products

5-Hydroxy-6,7-dimethoxyflavone, 5-hydroxy-7,8-dimethoxyflavone, 5-hydroxy-3,7-dimethoxyflavone, 3-hydroxy-5,7-dimethoxyflavone, 5-hydroxy-7,8-dimethoxyisoflavone and 5,7-dihydroxy-3-methoxyflavone and their derivatives have been synthesised to confirm the

O-methylation of flavonoids by cell-free extracts of calamondin orange

Cell-free extracts of calamondin orange (Citrus mitis) catalysed the O-methylation of almost all hydroxyls of a number of flavonoids, indicating the existence in citrus tissues of ortho, meta, para and 3-O-methyltransferases. The latter, hitherto unreported enzyme, catalysed the formation of 3-O-methyl ethers of galangin and quercetin. The stepwise O-methylation of a number of compounds, especially quercetin and quercetagetin, tends to suggest a coordinated sequence of O-methylations on the surface of a multienzyme complex. The methyl acceptor abilities of the flavonoid substrates used are discussed in relation to their hydroxyl substitution patterns and their negative electron density distribution.