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Urea, N-(4-chlorophenyl)-N'-(2-hydroxyethyl)-, also known as 4-chlorophenylurethane or 4-CPUE, is an organic compound with the chemical formula C9H11ClN2O2. It is a derivative of urea, featuring a 4-chlorophenyl group attached to one nitrogen atom and a 2-hydroxyethyl group attached to the other nitrogen atom. Urea, N-(4-chlorophenyl)-N'-(2-hydroxyethyl)- is primarily used as a chemical intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other specialty chemicals. Due to its reactivity and potential applications, it is essential to handle 4-CPUE with care, as it may have toxicological properties and require proper safety measures during its production and use.

66671-20-3

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66671-20-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 66671-20-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,6,7 and 1 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 66671-20:
(7*6)+(6*6)+(5*6)+(4*7)+(3*1)+(2*2)+(1*0)=143
143 % 10 = 3
So 66671-20-3 is a valid CAS Registry Number.

66671-20-3Relevant academic research and scientific papers

Synthesis and evaluation in vitro of 1-[2-(10-dihydroartemisininoxy) ethyl]-3-phenylurea derivatives as potential agents against cancer

Luo, Wei,Xia, Ming-Yu,Ikejima, Takashi,Li, Li-Hua,Guo, Chun

, p. 3170 - 3176 (2013/07/19)

In order to develop potent and selective anticancer agents, a series of novel artemisinin derivatives bearing urea moiety 1a-n were facilely synthesized herein and screened for their activities in vitro against ten human tumor cell lines (HeLa, MCF-7, U937, K562, HL60, HCT116, HepG2, A549, A375-S2, and HT1080). The pharmacological results indicated that some compounds showed excellent activity against cancer cell lines and good selectivity, especially the compound 1c which proved to be the most active against the cancer cells as well as distinctive patterns of selectivity.

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