50882-28-5

Basic information

• Product Name: PHENYL N-(4-CHLOROPHENYL)CARBAMATE
• Synonyms: PHENYL N-(4-CHLOROPHENYL)CARBAMATE
• CAS NO: 50882-28-5
• Molecular Formula: C₁₃H₁₀ClNO₂
• Molecular Weight: 247.68
• Mol File: 50882-28-5.mol
• Article Data: 20

Chemical Properties

• Melting Point: 185 °C
• Boiling Point: 343.8°Cat760mmHg
• Flash Point: 161.7°C
• Appearance: /
• Density: 1.329g/cm³
• Vapor Pressure: 6.85E-05mmHg at 25°C
• Refractive Index: 1.638
• PKA: 12.15±0.70(Predicted)
• CAS DataBase Reference: PHENYL N-(4-CHLOROPHENYL)CARBAMATE(CAS DataBase Reference)
• NIST Chemistry Reference: PHENYL N-(4-CHLOROPHENYL)CARBAMATE(50882-28-5)
• EPA Substance Registry System: PHENYL N-(4-CHLOROPHENYL)CARBAMATE(50882-28-5)

Safety Data

• Hazardous Substances Data: 50882-28-5(Hazardous Substances Data)

Usage

General Description

PHENYL N-(4-CHLOROPHENYL)CARBAMATE, also known as fenobucarb, is a carbamate insecticide used to control a variety of pests on crops such as rice, vegetables, and fruit trees. It acts by inhibiting the enzyme acetylcholinesterase, leading to the accumulation of the neurotransmitter acetylcholine at nerve junctions and causing paralysis in insects. Fenobucarb is highly effective against a wide range of pests, including aphids, beetles, and caterpillars, but it is also toxic to bees and other beneficial insects. Due to its potential environmental and health risks, fenobucarb is restricted for use in some countries and regulated in others.

InChI:InChI=1/C13H10ClNO2/c14-10-6-8-11(9-7-10)15-13(16)17-12-4-2-1-3-5-12/h1-9H,(H,15,16)

Upstream product

• 106-47-8 4-chloro-aniline 
• 1885-14-9 phenyl chloroformate 
• 102-09-0 bis(phenyl) carbonate 
• 1219-99-4 N,N'-bis(4-chlorophenyl)urea 
• 104-12-1 p-chlorphenylisocyanate 
• 108-95-2 phenol 
• 1202680-24-7 phenyl 4,5-dichloro-6-oxopyridazine-1(6H)-carboxylate 
• 932-96-7 N-methyl(p-chloroaniline) 
• 21368-28-5 4-chlorobenzoyl azide 

Downstream Products

• 1455-99-8 N-butyl-4-chlorobenzamide 
• 108-95-2 phenol 
• 3815-63-2 3-(4-chlorophenyl)-1-(4-tolyl)urea 
• 1350899-02-3 (E)-N-(4-chlorophenyl)-2-(4-hydroxy-3-methoxybenzylidene)hydrazinecarboxamide 
• 66671-20-3 N-(4-chloro-phenyl)-N'-(2-hydroxy-ethyl)-urea 
• 1428787-99-8 (E)-N⁴-(4-chlorophenyl)-N¹-(3-fluoro-4-(6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)quinoline-4-yloxy)benzylidene)semicarbazide 
• 449176-04-9 1-(4-chlorophenyl)-3-(6-nitrobenzo[d]thiazol-2-yl)urea 
• 65400-89-7 1,3-dimethyl-2,4,6-trioxo-hexahydro-pyrimidine-5-carboxylic acid 4-chloro-anilide 

Relevant articles and documents

3-(dimethylaminomethyl) piperidine-4-alcohol derivative as well as preparation method and pharmaceutical application thereof

The present invention provides compounds of formula (FWBF) or pharmaceutically acceptable salts thereof, in which the substituents are as defined in the specification, as well as a preparation method and pharmaceutical use thereof.

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Highly Regioselective Carbamoylation of Electron-Deficient Nitrogen Heteroarenes with Hydrazinecarboxamides

The use of hydrazinecarboxamides as a new class of carbamoylating agents has been established through the dehydrazinative Minisci reaction of electron-deficient nitrogen heteroarenes. A wide range of electron-deficient nitrogen heteroarenes, including isoquinoline, quinoline, pyridine, phenanthridine, quinoxaline, and phthalazine, underwent copper/acid-catalyzed oxidative carbamoylation with hydrazinecarboxamide hydrochlorides to afford structurally diverse nitrogen-heteroaryl carboxamides as single regioisomers in moderate to excellent yields. The functional group tolerance was substantially demonstrated in the direct carbamoylation of quinine obviating multistep sequences involving protecting groups and prefunctionalization of the heterocycle.