666735-83-7Relevant academic research and scientific papers
Synthesis and psychotropic evaluation of some new N-substitutedbenzothia/ oxazepinylphenothiazines
Bajaj, Kiran,Srivastava,Kumar, Ashok
, p. 157 - 161 (2007/10/03)
A number of N-[2-substitutedaryl-3-substitutedarylaminomethylene-2, 3-dihydro-1,5-benzothia/oxazepin-4-yl]phenothiazines 4a-p and 4a′-p′ have been synthesized from N-[2-substitutedaryl-2, 3-dihydro-1, 5-benzothia/oxazepin-4-yl]phenothiazines by Mannich reaction, on the 3 rd position of benzothia/oxazepine ring. The structure of these compounds have been confirmed by IR, 1H NMR and Mass analysis. The newly synthesized compounds have been evaluated for their psychotropic activities and acute toxicity studies. Compound 4i is found to be most potent compound of this series.
