6672-69-1

Basic information

• Product Name: 5H-Dibenz[c,e]azepine, 6,7-dihydro-
• Synonyms: 5H-Dibenz[c,e]azepine, 6,7-dihydro-;6,7-dihydro-5H-dibenz(c,e)azepine;5,7-Dihydro-6H-dibenzo[c,e]azepine;RO-2-3421;6,7-dihydro-5H-dibenzo[c,e]azepine
• CAS NO: 6672-69-1
• Molecular Formula: C₁₄H₁₃N
• Molecular Weight: 195.26
• Mol File: 6672-69-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 361.1°C at 760 mmHg
• Flash Point: 186.8°C
• Appearance: /
• Density: 1.085g/cm³
• Vapor Pressure: 2.13E-05mmHg at 25°C
• Refractive Index: 1.602
• CAS DataBase Reference: 5H-Dibenz[c,e]azepine, 6,7-dihydro-(CAS DataBase Reference)
• NIST Chemistry Reference: 5H-Dibenz[c,e]azepine, 6,7-dihydro-(6672-69-1)
• EPA Substance Registry System: 5H-Dibenz[c,e]azepine, 6,7-dihydro-(6672-69-1)

Safety Data

• Hazardous Substances Data: 6672-69-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H13N/c1-3-7-13-11(5-1)9-15-10-12-6-2-4-8-14(12)13/h1-8,15H,9-10H2

Upstream product

• 58335-98-1 6-benzyl-6,7-dihydro-5H-dibenz[c,e]azepine 
• 3864-08-2 diphenimide 
• 31638-37-6 6,7-dihydro-5H-dibenzicazepine-7-one 
• 6747-35-9 2-carboxy-2'-(aminocarboxyl)-1,1'-biphenyl 
• 6050-13-1 biphenyl-2,2'-dicarboxylic acid anhydride 
• 5807-64-7 diphenic acid dimethyl ester 
• 38274-14-5 2,2'-bis-(bromomethyl)-1,1'-biphenyl 
• 3594-90-9 2,2'-bis(hydroxymethyl)biphenyl 
• 42773-01-3 2,2'-(2-azapropane-1,3-diyl)-1,1'-biphenyl-N-hydroxide 

Relevant articles and documents

Biocatalytic Routes to Enantiomerically Enriched Dibenz[c,e]azepines

Biocatalytic retrosynthetic analysis of dibenz[c,e]azepines has highlighted the use of imine reductase (IRED) and ω-transaminase (ω-TA) biocatalysts to establish the key stereocentres of these molecules. Several enantiocomplementary IREDs were identified

Asymmetric activation of tropos catalysts in the stereoselective catalytic conjugate additions of R2Zn to α,β-enones: An efficient synthesis of (-)-muscone

The preparation of a new phosphoramidite starting from (R)-BINOL and a biphenylamine is presented. In such a compound the chirality is due only to atropisomerism and this molecule possesses a flexible biphenylamine residue. Therefore it can work as a tropos catalyst. The catalytic efficiency of this new phosphoramidite has been tested in some asymmetric conjugate additions of dialkylzinc reagents to α,β-enones and compared with that of an analogous already known non-tropos ligand. Interestingly, while comparable results were obtained in the addition of ZnEt2 to chalcone and cyclohexenone, in the case of the addition of ZnMe2 to (E)-cyclopentadec-2-en-1-one, the new ligand provides (-)-muscone, a valuable ingredient of the perfume industry, in 84% ee, while the non-tropos ligand gives a much lower (57%) ee value. Graphical Abstract

A facile synthesis of 6-alkyl-6,7-dihydro-5H-dibenz[c,e]azepines: Potent hypolipidemics

6-Alkyl-6,7-dihydro-5H-dibenz[c,e]azepines were synthesized in two steps in 63-88% overall yield by utilizing an efficient borane-tetrahydrofuran reduction of imides.