66727-77-3

Upstream product

• 2169-69-9 ethyl (E)-2-cyano-3-phenyl-2-propenoate 
• 614-16-4 Benzoylacetonitrile 
• 20413-05-2 2-benzoyl-3-phenylacrylonitrile 
• 105-56-6 ethyl 2-cyanoacetate 

Downstream Products

• 132744-73-1 2-amino-5-cyano-4,6-diphenyl-4H-pyran-3-(2-pyridylamide) 
• 61378-38-9 2,4,6-triphenyl-1,4-dihydropyridine-3,5-dicarbonitrile 
• 132819-59-1 3-cyano-2,4-diphenyl-5,6,7,8-tetrahydro-4H-pyrano<2,3-b>pyridine-5,7-dione 
• 132744-77-5 2-amino-5-cyano-4,6-diphenyl-4H-pyran-3-carboxylic acid 
• 107199-98-4 5-Cyano-3-ethoxycarbonyl-4,6-diphenyl-3,4-dihydro-pyrid-2-one 
• 132819-66-0 6-cyano-2-trichloro-4(3H)-oxo-5,7-diphenyl-5H-pyrano<2,3-d>pyrimidine 
• 588-64-7 benzaldehyde phenylhydrazone 
• 64646-31-7 2-amino-4,6-diphenyl-4H-pyran-3,5-dicarbonitrile 
• 132819-60-4 2-(N-acetyl-N-carbethoxymethyl)-3-carbethoxy-5-cyano-4,6-diphenyl-4H-pyran 
• 132819-62-6 3-cyano-5-carbethoxy-2,4-diphenyl-6-(pyrrolo-2,4-dione)pyran 
• 132819-63-7 7-cyano-6,8-diphenyl-2,3,4,5-tetrahydro-6H-1,4-methanopyrano<2,3-b>azepin-3,5,10-trione 
• 132744-79-7 2-Diethylaminomethyl-4-oxo-5,7-diphenyl-3-pyridin-2-yl-3,5-dihydro-4H-pyrano[2,3-d]pyrimidine-6-carbonitrile 
• 132744-76-4 2-Dimethylaminomethyl-4-oxo-5,7-diphenyl-3-pyridin-2-yl-3,5-dihydro-4H-pyrano[2,3-d]pyrimidine-6-carbonitrile 
• 132744-75-3 2-chloromethyl-6-cyano-4(3H)-oxo-5,7-diphenyl-3-(2-pyridyl)pyrano<3,2-b>pyrimidine 

Relevant academic research and scientific papers

Reactions with Heterocyclic β-Enaminoesters: A Novel Synthesis of 2-Amino-3-ethoxycarbonyl-(4H)-pyrans

The reaction of ethyl cyanoacetate with α-cyanochalcone (1) leads to the formation of β-enaminoesters (3) via Michael addition.Compound 3 reacts with phenylmagnesium bromide to give the β-enaminoketone 5.Acetylation of 3 gives the acetyl product 4.Each of compounds 1 and 3 reacts with malononitrile to give β-enaminonitrile 6.Phenylhydrazine reacts with 3 to give the hydrazone 7.Similarly 3-phenyl-5-aminopyrazole reacts with 3 to give the Schiff base 8. - Keywords: Enaminopyrans; Michael addition; Pyrans, cleavage of