61378-38-9

Basic information

• Product Name: 2,4,6-triphenyl-1,4-dihydropyridine-3,5-dicarbonitrile
• Synonyms: 2,4,6-triphenyl-1,4-dihydropyridine-3,5-dicarbonitrile
• CAS NO: 61378-38-9
• Molecular Weight: 359.43
• Mol File: 61378-38-9.mol

Chemical Properties

• CAS DataBase Reference: 2,4,6-triphenyl-1,4-dihydropyridine-3,5-dicarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-triphenyl-1,4-dihydropyridine-3,5-dicarbonitrile(61378-38-9)
• EPA Substance Registry System: 2,4,6-triphenyl-1,4-dihydropyridine-3,5-dicarbonitrile(61378-38-9)

Safety Data

• Hazardous Substances Data: 61378-38-9(Hazardous Substances Data)

Upstream product

• 1823-99-0 3-amino-3-phenylacrylonitrile 
• 92-29-5 hydrobenzamide 
• 64646-31-7 2-amino-4,6-diphenyl-4H-pyran-3,5-dicarbonitrile 
• 39487-54-2 1-((dimethylamino)(phenyl)methyl)naphthalen-2-ol 
• 60375-56-6 (E)-3-amino-3-phenylacrylonitrile 
• 100-52-7 benzaldehyde 
• 98-88-4 benzoyl chloride 
• 20413-05-2 2-benzoyl-3-phenylacrylonitrile 
• 614-16-4 Benzoylacetonitrile 
• 66727-77-3 Ethyl 2-amino-5-cyano-4,6-diphenyl-4H-pyran-3-carboxylat 

Downstream Products

• 92082-39-8 2,4,6-triphenylpyridine-3,5-dicarbonitrile 

Relevant articles and documents

Reactions of naphthalen-2-ol Mannich bases with β-aminoacrylonitriles and methyl 3-morpholinoacrylate

[InlineMediaObject not available: see fulltext.]3-Amino-2,3-dihydro-1H-benzo[f]chromenes and 2-[(2-hydroxynaphthalen-1-yl)methyl]-2,3-dihydro-1H-benzo[f]chromene-2-carbonitriles were obtained via the reaction of naphthalen-2-ol Mannich bases with β-aminoa

β-enaminonitriles in heterocyclic synthesis: Synthesis of new 1,4-dihydropyridine, pyrazolo[1,5-a]pyrimidine, aminothiophene and pyridine derivatives

Utility of 3-aminocinnamonitrile (1) in the synthesis of new 1,4-dihydropyridine, pyrazolo[1,5-a]pyrimidine, aminothiophene and pyridine derivatives is reported.

Studies on β-Enaminonitriles: Part I- Benzoylation in Presence of Sodium in Benzene

Sodium dust in benzene brings about an unusual reductive decyanation of β-aminocrotononitrile (1) to afford N-benzoylisopropylamine (2) as the major product, for which a tentative mechanism involving radical addition has been suggested.Benzoylation of β-aryl-β-aminoacrylonitriles (10, 11 and 12), however, under somilar conditions furnish a complex mixture of compounds, namely, β-aryl-β-amino-α-benzoylacrylonitriles (14, 18 and 22), pyrimidines (13, 17 and 21), β-ketonitriles (19, 20 and 23) and benzamide (16) in varying yields but in no case the formation of the corresponding reductive decyanation products have been observed.

SYNTHESIS OF 3,5-DICYANO-4-PHENYL-2,6-BIS(4-p-TERPHENYLYL)-1,4-DIHYDROPYRIDINE. AN ATTEMPT AT EXTENDING THE HANTZSCH SYNTHESIS

The 3-oxopropanenitrile IIIc, prepared from 4-acetyl-p-terphenyl (IV) by the sequence IV -> V -> VI -> IIIc, reacts with benzaldehyde and ammonium acetate in acetic acid to give the Hantzsch dihydropyridine VIIc and the corresponding pyridine derivative VIIIc.The alternative cyclocondensation of benzylidene derivative IIc and 3-oxopropanenitrile IIIc in the presence of ammonium acetate exclusively gives the pyridine derivative VIIIc.Rate of thermal and oxidative aromatizations of the 1,4-dihydropyridine derivatives, VIIa-VIIc -> VIIIa-VIIIc, decreases in the order VIIc > VIIb > VIIa.Mechanism of these transformations and spectral characteristics of compounds VIIc and VIIIc are discussed with regard to their molecular structure.

Ring Transformations of 4H-Pyrans. Pyridines from 2-Amino-4H-Pyrans

Ring transformations of 4H-pyrans into pyridines are reported.Treatment of 2-amino-4,6-diaryl-3,5-dicyano-4H-pyrans (I) with nitrosylsulfuric acid brings about their transformation into 3,5-dicyano-4,6-diaryl-2-pyridones (VI) which can also be obtained fr