66729-02-0

Basic information

• Product Name: (2R,3S)-3-hydroxy-2-methyl-butanoic acid
• Synonyms: (2R,3S)-3-hydroxy-2-methyl-butanoic acid;Erythronilic acid
• CAS NO: 66729-02-0
• Molecular Formula: C₅H₁₀O₃
• Molecular Weight: 0
• Mol File: 66729-02-0.mol

Chemical Properties

• Boiling Point: 242.8°C at 760 mmHg
• Flash Point: 114.9°C
• Appearance: /
• Density: 1.136g/cm³
• Vapor Pressure: 0.00567mmHg at 25°C
• Refractive Index: 1.455
• CAS DataBase Reference: (2R,3S)-3-hydroxy-2-methyl-butanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3S)-3-hydroxy-2-methyl-butanoic acid(66729-02-0)
• EPA Substance Registry System: (2R,3S)-3-hydroxy-2-methyl-butanoic acid(66729-02-0)

Safety Data

• Hazardous Substances Data: 66729-02-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(2R,3S)-3-hydroxy-2-methyl-butanoic acid is used as a chiral building block for the synthesis of drugs and other bioactive compounds. Its unique stereochemistry allows for the creation of enantiomerically pure compounds, which is crucial for the development of effective and safe medications.
Used in Cosmetic Industry:
In the cosmetic industry, (2R,3S)-3-hydroxy-2-methyl-butanoic acid is utilized as a chiral building block for the synthesis of various cosmetic ingredients. Its ability to create enantiomerically pure compounds contributes to the development of high-quality and innovative cosmetic products.
Used in Medical Applications:
(2R,3S)-3-hydroxy-2-methyl-butanoic acid has potential medical applications, particularly in the management of certain metabolic disorders. Its presence as a natural byproduct of valine metabolism suggests a role in regulating metabolic pathways.
Used as a Biomarker:
Furthermore, (2R,3S)-3-hydroxy-2-methyl-butanoic acid has potential as a biomarker for various diseases. Its detection and quantification in biological samples could aid in the diagnosis, monitoring, and treatment of certain conditions.

InChI:InChI=1/C5H10O3/c1-3(4(2)6)5(7)8/h3-4,6H,1-2H3,(H,7,8)/t3-,4+/m1/s1

Upstream product

• 609-14-3 2-acetylpropanoic acid ethyl ester 
• 75-07-0 acetaldehyde 
• 535-11-5 Ethyl 2-bromopropionate 
• 684-84-4 2-methyl-1,3-butanediol 
• 124-38-9 carbon dioxide 
• 7732-18-5 water 
• 27372-03-8 ethyl 3-hydroxy-2-methylbutyrate 
• 219783-12-7 [2R,3S,1'S,2'S]-(+)-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-3-hydroxy-N,2-dimethyl-butanamide 
• 80-59-1 Tiglic acid 
• 90033-09-3 N-(2-t-butyldimethylsiloxyethyl)-2-methylacetoacetamide 
• 34293-67-9 methyl 3-(R)-hydroxy-2-(S)-methylbutanoate 
• 17094-21-2 2-methyl-acetoacetic acid methyl ester 
• 468756-88-9 (4R,2'R,3'S)-N-(3-hydroxy-2-methylbutanoyl)-4-benzyl-2-oxazolidinone 

Downstream Products

• 80-59-1 Tiglic acid 
• 7732-18-5 water 
• 59056-73-4 (2S,3S,7R/S)-3,7-dimethylpentadecan-2-ol 

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