66752-03-2

Upstream product

• 16439-95-5 4-phenyl-2,3-dihydro-1H-1,5-benzodiazepin-2-one 

Downstream Products

• 124411-59-2 C₃₁H₂₂Br₂N₄O₂ 
• 374629-51-3 (2-oxo-4-phenyl-2,3-dihydro-1H-benzo[b][1,4]diazepin-3-ylsulfanyl)-acetic acid ethyl ester 
• 374629-47-7 3-(2-amino-ethylsulfanyl)-4-phenyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one 
• 374629-49-9 1-(2-oxo-4-phenyl-2,3-dihydro-1H-1,5-benzodiazepin-3-yl)guanidine 
• 374629-52-4 (2-oxo-4-phenyl-2,3-dihydro-1H-benzo[b][1,4]diazepin-3-ylamino)-acetic acid ethyl ester 
• 955958-01-7 3-cyano-4-phenyl-1(H)-(1,5)benzodiazepin-2-one 

Relevant academic research and scientific papers

Nucleophilic substitution in 1,5-benzodiazepin-2-ones

The reaction of 3-bromo-4-phenyl-2,3-dihydro-1H -1,5-benzodiazepin-2-one with cyclic amines gives 3-aminoalkyl-4-phenyl-2,3-dihydro-1H-1,5-benzodiazepin-2-one. Thiazolo[4, 5-b][1,5]benzodiazepine was isolated along with the substitution product when thiou

Metal-free oxidative ring contraction of benzodiazepinones: an entry to quinoxalinones

A novel and practical synthesis of 3-benzoylquinoxalin-2(1H)-ones from benzodiazepin-2-ones in two steps from commercially available starting materials is reported. The reaction was achieved in the presence of N-bromosuccinimide in DMSO which served both

Synthesis of new 3-substituted and spiro 1,5-benzodiazepin-2-ones under phase-transfer catalysis conditions

1,3-Dihydro-4-phenyl-1,5-benzodiazepin-2-one 1 was treated with bromine in 1:1 molar ratio to get the corresponding 3-bromo derivative 2 which in turn reacted with different nucleophiles to get the corresponding 3-substituted derivatives 3-11. The cyclize

ETUDE DE LA REACTIVITE DU BIS--1,1' METHANE

Study of the reactivity of Bis-1,1'-methane allowed us to throw into relief different reactive site of this type of molecule.