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CAS

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374629-49-9

1-(2-oxo-4-phenyl-2,3-dihydro-1H-1,5-benzodiazepin-3-yl)guanidine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 374629-49-9 Structure

  • Basic information

    1. Product Name: 1-(2-oxo-4-phenyl-2,3-dihydro-1H-1,5-benzodiazepin-3-yl)guanidine
    2. Synonyms: 1-(2-oxo-4-phenyl-2,3-dihydro-1H-1,5-benzodiazepin-3-yl)guanidine
    3. CAS NO:374629-49-9
    4. Molecular Formula:
    5. Molecular Weight: 293.328
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 374629-49-9.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-(2-oxo-4-phenyl-2,3-dihydro-1H-1,5-benzodiazepin-3-yl)guanidine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-(2-oxo-4-phenyl-2,3-dihydro-1H-1,5-benzodiazepin-3-yl)guanidine(374629-49-9)
    11. EPA Substance Registry System: 1-(2-oxo-4-phenyl-2,3-dihydro-1H-1,5-benzodiazepin-3-yl)guanidine(374629-49-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 374629-49-9(Hazardous Substances Data)

374629-49-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 374629-49-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,4,6,2 and 9 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 374629-49:
(8*3)+(7*7)+(6*4)+(5*6)+(4*2)+(3*9)+(2*4)+(1*9)=179
179 % 10 = 9
So 374629-49-9 is a valid CAS Registry Number.

374629-49-9Downstream Products

374629-49-9Relevant articles and documents

Hetaryl-1,5 Benzodiazepines—Part I: Synthesis of 3-pyrimidinyl- and Imidazolyl-1,5-benzodiazepines

Khodairy, Ahmed,Ahmed, Eman A.,Abdel Ghany, Hossam

, p. 242 - 247 (2017)

Nucleophilic substitution of 3-bromo-4-phenyl-1H-[1,5]benzodiazepin-2-one (1) with thiourea or guanidine in presence of potassium carbonate afforded 1,5-benzodiazepin-3-ylimidothiocarbamate 2 or 1,5-benzodiazepin-3-ylguanidine 3, respectively. Pyrimidylthiobenzodiazepines 5, 6, 7, 8, 9, 10, 11, 12, 13 were obtained via the reaction of compound 2 with malononitrile dimer, diethyl malonate, methylenemalononitriles, or a mixture of an aldehyde and β-keto esters or acetylacetone, catalyzed using ceric ammonium nitrate. Reaction of compound 2 or 3 with α-halo esters, nitriles, and/or ketones afforded imidazoles 14, 15, 16, 17, 18, 19, 20, respectively.

Synthesis of new 3-substituted and spiro 1,5-benzodiazepin-2-ones under phase-transfer catalysis conditions

Abdel-Ghany,El-Sayed,Khodairy,Salah

, p. 2523 - 2535 (2007/10/03)

1,3-Dihydro-4-phenyl-1,5-benzodiazepin-2-one 1 was treated with bromine in 1:1 molar ratio to get the corresponding 3-bromo derivative 2 which in turn reacted with different nucleophiles to get the corresponding 3-substituted derivatives 3-11. The cyclize

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