668485-63-0

Upstream product

• 181059-55-2 (S)-3-Benzo[1,3]dioxol-5-yl-4-((S)-4-benzyl-2-oxo-oxazolidin-3-yl)-4-oxo-butyric acid tert-butyl ester 
• 181059-54-1 (S)-3-(2-Benzo[1,3]dioxol-5-yl-acetyl)-4-benzyl-oxazolidin-2-one 
• 250583-00-7 (S)-2-Benzo[1,3]dioxol-5-yl-succinic acid 4-tert-butyl ester 
• 6845-81-4 3,4-methylenedioxyphenylacetyl chloride 
• 2861-28-1 1,3-benzodioxole-5-acetic acid 
• 181059-56-3 (S)-2-Benzo[1,3]dioxol-5-yl-3-chlorocarbonyl-propionic acid methyl ester 

Downstream Products

• 181228-61-5 (2S,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-5-oxo-1-(2-propoxy-ethyl)-pyrrolidine-3-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Synthesis of enantiomerically pure pyrrolidinones as endothelin receptor antagonists

Enantiomerically pure pyrrolidinones were synthesized as endothelin receptor antagonists. A [2 + 2] cycloaddition of an imine and an enantiomerically pure acid chloride gave two diastereomeric β-lactams which were separated and rearranged to give the enantiomerically pure pyrrolidinones which could be reduced to give the corresponding pyrrolidines.