6685-76-3

Usage

Uses

Used in Pharmaceutical Industry:
Phenylguanidine hydrogen carbonate is used as a reagent in the production of various pharmaceuticals. Its ability to act as a catalyst in the synthesis of certain organic compounds makes it a valuable component in the development of new drugs.
Used in Dye Industry:
This chemical compound is also utilized in the production of dyes, where its reactivity and solubility properties contribute to the creation of a wide range of colorants.
Used in Organic Synthesis:
Phenylguanidine hydrogen carbonate is used as a catalyst in the synthesis of certain organic compounds, facilitating chemical reactions and improving the efficiency of organic synthesis processes.
Used as a Corrosion Inhibitor:
In certain industrial processes, phenylguanidine hydrogen carbonate is employed as a corrosion inhibitor, helping to prevent the degradation of materials and equipment, thereby extending their lifespan and reducing maintenance costs.

Upstream product

• 13140-47-1 N-n-propyl-N'-phenylthiourea 
• 129226-13-7 4-Phenyl-5-[(E)-propylimino]-4,5-dihydro-[1,2,4]thiadiazol-3-ylamine 
• 420-04-2 CYANAMID 
• 497-19-8 sodium carbonate 
• 62-53-3 aniline 

Downstream Products

• 453547-85-8 (4-imidazo[1,2-b]pyridazin-3-yl-pyrimidin-2-yl)-phenyl-amine 
• 453548-00-0 [4-(6-methoxy-imidazo[1,2-b]pyridazin-3-yl)-pyrimidin-2-yl]-phenyl-amine 
• 453547-92-7 [4-(2-methyl-imidazo[1,2-b]pyridazin-3-yl)-pyrimidin-2-yl]-phenyl-amine 
• 403791-28-6 2-anilino-4-(1-ethyl-2-methylimidazol-5-yl)pyrimidine 
• 600639-05-2 2-anilino-4-(1-isopropyl-2-methoxymethylimidazol-5-yl)pyrimidine 
• 1009056-19-2 [4-(1,1-dimethoxyethyl)pyrimidin-2-yl]phenylamine 
• 802534-50-5 ethyl 1-methyl-8-(phenylamino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylate 
• 1203555-45-6 6-(2,6-dichlorophenyl)-5,6-dihydro-2-(phenylamino)pyrido[2,3-d]pyrimidin-7(8H)-one 
• 1203555-48-9 5,6-dihydro-2-(phenylamino)-6-o-tolylpyrido[2,3-d]pyrimidin-7(8H)-one 
• 1203555-46-7 5,6-dihydro-6-(naphthalen-1-yl)-2-(phenylamino)pyrido[2,3-d]pyrimidin-7(8H)-one 
• 1225273-60-8 ethyl 1-phenyl-8-(phenylamino)-4,5-dihydro-1H-pyrazolo-[4,3-h]quinazoline-3-carboxylate 
• 1335491-06-9 4-(2-methoxyphenyl)-N-phenyl-1,3,5-triazine-2-amine 
• 930581-48-9 {4-[2-(phenyl(methyl)amino)-4-methylthiazol-5-yl]pyrimidin-2-yl}-N-phenylamine 
• 1333391-33-5 {4-[2-(o-tolyl(methyl)amino)-4-methylthiazol-5-yl]pyrimidin-2-yl}-N-phenylamine 

Relevant academic research and scientific papers

Method for preparing mepanipyrim

The invention provides a preparation method of mepanipyrim and belongs to the field of pesticide chemical synthesis technologies. The preparation method of the mepanipyrim comprises the following steps: firstly, reacting phenyl guanidine salt with ethyl acetoacetate so as to prepare phenylamino pyrimidone, reacting the phenylamino pyrimidone with phosphorus oxychloride so as to prepare 2-chloro-pyrimidine phenylamine; subsequently, carrying out coupling and crossing reaction between the 2-chloro-pyrimidine phenylamine and alkyne so as to prepare mepanipyrim. The preparation method of mepanipyrim has the advantages that the used raw materials and reagents are cheap and easily available; the reaction process is simple, the reaction conditions are mild, the cost is low, the yield is high, a good condition is created for industrial large-scale production and commercialization of the products.

Synthesis of novel thiazolyl-pyrimidines and their anticancer activity in vitro

A series of novel compounds 7-43 were prepared via the condensation of enaminones 4a-h and the guanidines carbonate 6a-f. The structures of these newly synthesized compounds were confirmed by 1H-NMR, MS, EA and IR. All the compounds were tested for their cytotoxic activity in vitro against human cancer cell lines including Ishikawa, A549, BEL-7404, SPC-A-01 and SGC-7901. Most of them showed moderate cytotoxic against the tested cell lines. Among them, the most potent compounds 9 and 30 exhibited more efficient activity against Ishikawa, A549. Thiazolyl-pyrimidines were synthesized by the general pyrimidine condensation of Bredereck and their in-vitro anticancer activities were evaluated. Copyright

Substituted benzene derivatives useful as neuraminidase inhibitors

A compound of the Formula (I): STR1 or pharmaceutically-suitable salts or prodrug forms thereof, wherein: n is 0-1; m is 0; p is 0-1; R1 is --CO2 H; R2 is selected from the group consisting of H, --OH, and --NH2 ; R3 is H; R4 is --C(O)NHR8 ; R5 is --NHC(R6)NH2 R6 is selected from the group consisting of =NH, =NOH, =NCN, =O, and =S; and R8 is selected from the group consisting of C1 -C4 linear or branched alkyl substituted with 0-3 halogens on each carbon.

Process for the production of guanidine derivatives

A process for the production of phenylguanidine carbonate and hydrogencarbonate by reacting aqueous cyanamide with aniline hydrochloride within a specified pH range, combining the reaction mixture with an alkali metal carbonate or hydrogencarbonate, and separating the crystalline product.