66869-82-7

Basic information

• Product Name: 1-(1-phenyl-1H-imidazol-2-yl)ethan-1-one
• Synonyms: 1-(1-phenyl-1H-imidazol-2-yl)ethan-1-one
• CAS NO: 66869-82-7
• Molecular Weight: 186.213
• Mol File: 66869-82-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(1-phenyl-1H-imidazol-2-yl)ethan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-phenyl-1H-imidazol-2-yl)ethan-1-one(66869-82-7)
• EPA Substance Registry System: 1-(1-phenyl-1H-imidazol-2-yl)ethan-1-one(66869-82-7)

Safety Data

• Hazardous Substances Data: 66869-82-7(Hazardous Substances Data)

Upstream product

• 1696-20-4 4-acetylmorpholine 
• 7164-98-9 1-phenylimidazole 
• 141-78-6 ethyl acetate 
• 127-19-5 N,N-dimethyl acetamide 

Downstream Products

• 1428368-38-0 1-(4,5-diphenylimidazo[1,5-a]quinolin-1-yl)ethan-1-one 

Relevant articles and documents

Organocatalytic Enantioselective Conjugate Alkynylation of β-Aminoenones: Access to Chiral β-Alkynyl-β-Amino Carbonyl Derivatives

Readily available potassium alkynyltrifluoroborates were used for organocatalytic asymmetric conjugate alkynylation of β-enaminones. The interception of a modified binaphthol catalyst and in situ generated organodifluoroboranes proved important to access functionalized β-alkynyl-β-amino carbonyls and derivatives with improved chemo-reactivity and enantio-induction. Mechanistic studies revealed the impact of molecular sieves on efficiency and stereocontrol. The products undergo additional functionalization to yield a diverse set of valuable β-alkynyl-β-amino carbonyl scaffolds.

Production of optically active aromatic compounds having nitrogen atoms in a ring structure comprising

PROBLEM TO BE SOLVED: To provide a production method for obtaining an optically active aromatic compound having a cyclic structure including a nitrogen atom, in which a modified group can be removed while keeping a high yield and optical purity, with a high yield in a high enantioselective manner.SOLUTION: An aromatic compound described below is used as a substrate: in the aromatic compound, an amino group expressed by -NHR11 (where R11 is an arene sulfonyl group) is bonded to one of two carbon atoms constituting a benzene ring and adjoining to each other, and -R13-CHR15-C(=O)-Z (where R13 represents a methylene or an ethylene which may have a substituent, R15 represents a hydrogen atom, an alkyl group which may have a substituent, or a cycloalkyl group which may have a substituent, and Z represents a heteroaryl group which may have a substituent) is bonded to the other carbon atom. The substrate is made to react in a system to which N-spiro C2 axis asymmetric quaternary ammonium iodide and an oxidizing agent are supplied so as to obtain an aromatic compound having a cyclic structure including a nitrogen atom derived from the above amino group.