66883-92-9

Basic information

• Product Name: [4-(morpholin-4-yl)benzylidene]propanedinitrile
• Synonyms: propanedinitrile, 2-[[4-(4-morpholinyl)phenyl]methylene]-
• CAS NO: 66883-92-9
• Molecular Formula: C₁₄H₁₃N₃O
• Molecular Weight: 239.2725
• Mol File: 66883-92-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 457.3°C at 760 mmHg
• Flash Point: 230.4°C
• Density: 1.215g/cm³
• Vapor Pressure: 1.5E-08mmHg at 25°C
• Refractive Index: 1.61
• CAS DataBase Reference: [4-(morpholin-4-yl)benzylidene]propanedinitrile(CAS DataBase Reference)
• NIST Chemistry Reference: [4-(morpholin-4-yl)benzylidene]propanedinitrile(66883-92-9)
• EPA Substance Registry System: [4-(morpholin-4-yl)benzylidene]propanedinitrile(66883-92-9)

Safety Data

• Hazardous Substances Data: 66883-92-9(Hazardous Substances Data)

Usage

General Description

[4-(morpholin-4-yl)benzylidene]propanedinitrile, also known as MBPD, is a chemical compound with the molecular formula C13H12N2O. It is a yellow solid that is primarily used as a component in the synthesis of organic compounds. MBPD has been studied for its potential applications in materials science and pharmaceutical research. Its unique chemical structure and reactivity make it a versatile building block for the creation of new molecules with varied properties. However, like many organic compounds, MBPD should be handled with caution and proper safety measures should be taken when working with it in a laboratory setting.

Upstream product

• 459-57-4 4-fluorobenzaldehyde 
• 1204-86-0 4-(4-morpholinyl)benzaldehyde 
• 109-77-3 malononitrile 
• 110-91-8 morpholine 
• 2826-22-4 4-fluorobenzylidenemalononitrile 

Downstream Products

• 1174730-38-1 7-amino-6-cyano-5-[4-(4-morpholinyl)phenyl]-2-thioxopyrido[2,3-d]pyrimidin-4(1H)-one 
• 1369588-78-2 5-amino-1-benzyl-6,8-dicyano-7-[4-(4-morpholinyl)phenyl]-1H-[1,2,4]triazolo[1,5-a]pyridin-4-ium-2-thiolate 
• 1369588-80-6 5-amino-6,8-dicyano-7-[4-(4-morpholinyl)phenyl]-1-(prop-2-en-1-yl)-1H-[1,2,4]triazolo[1,5-a]pyridin-4-ium-2-thiolate 
• 1369588-75-9 5-amino-6,8-dicyano-1-methyl-7-[4-(4-morpholinyl)phenyl]-1H-[1,2,4]triazolo[1,5-a]pyridin-4-ium-2-thiolate 
• 812666-84-5 5-amino-3-oxo-2-[4-(morpholin-4-yl)benzylidenyl]-7-[4-(morpholin-4-yl)phenyl]-2,3-dihydro-7H-thiazolo[3,2-a]pyridin-6,8-dicarbonitrile 

Relevant articles and documents

Ultrasound-assisted and efficient knoevenagel condensation reaction catalyzed by silica sodium carbonate nanoparticles

An efficient and ultrasound-assisted route to the synthesis of arylidene malononitriles/methylciano- or ethylciano acetates in a one-pot reaction catalyzed by silica sodium carbonate nanoparticles (SSC NPs) is described. In this reaction, SSC NPs demonstrated high efficiency as catalyst to obtain target products. By this achievement, a wide range of α,β-unsaturated compounds as Knoevenagel condensation products with good to excellent yields are obtained from reaction between numerous arylaldehydes, and malononitrile, methyl cianoacetate or ethyl cianoacetate. Target products which prepared in high yield and high purity can be candidate as important biologically active molecules. This method is an easy, cheap, rapid and highly efficient for the synthesis of desired products. In addition, capability of catalyst to separate from reaction mixture and reuse in further runs and being compatible with green chemistry are considered as other advantages of this procedure. All products were deduced from their FT-IR and FT-NMR spectroscopic and elemental analysis data.

New pyridinecarbonitriles from fluoro arylpropenones

The facile synthetic approaches to 3-pyridinecarbonitriles are described.The first approach involves the base-catalyzed transformation of 4-hydroxy-1,1-cyclohexanedicarbonitrile 2a into 4a, b.The other route involves the base-catalyzed multi-step one-pot reaction of aryl methyl ketones with the appropriate arylidenemalononitriles 6, 11a, b.Careful study of the synthesis of 2a, b from 1a, b revealed the importance of controlling the reaction conditions.Thus, 1,7-dioxo-4,4-heptanedicarbonitriles 3a, b or 3-pyridinecarbonitrile 4a were obtained in addition to the desired 2a, b under different basic conditions.

Catalyst compositions for trimerizing organic isocyanates

Disclosed are novel compositions capable of catalytically trimerizing organic isocyanates said compositions comprising solutions of the reaction products obtained by reacting in an inert solvent in substantially equimolar proportions electron-rich ketene-aminals with electron-poor olefins having the respective formulae (I) and (II) STR1 The variously substituted electron-rich ketene-aminals (I), as the name implies, have high electron density associated with the double bond because of the two tertiary amine groups while the electron-poor olefins (II) have the opposite situation due to the presence of electron withdrawing substituents R9 and R10. Also disclosed is an improved process for trimerizing organic isocyanates using the above catalyst compositions including the preparation of polyisocyanurate polymers and isocyanurate-modified polyisocyanates.