669-81-8

Basic information

• Product Name: 1,2,6-Trimethylpiperidine
• Synonyms: 1,2,6-TRIMETHYLPIPERIDINE; Piperidine, 1,2,6-trimethyl-
• CAS NO: 669-81-8
• Molecular Formula: C8H17N
• Molecular Weight: 127.23
• Mol File: 669-81-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 134.5°C at 760 mmHg
• Flash Point: 28.5°C
• Appearance: /
• Density: 0.807g/cm³
• Vapor Pressure: 8.07mmHg at 25°C
• Refractive Index: 1.43
• PKA: 10.56±0.10(Predicted)
• CAS DataBase Reference: 1,2,6-Trimethylpiperidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,6-Trimethylpiperidine(669-81-8)
• EPA Substance Registry System: 1,2,6-Trimethylpiperidine(669-81-8)

Safety Data

• Hazardous Substances Data: 669-81-8(Hazardous Substances Data)

Usage

General Description

1,2,6-Trimethylpiperidine is a chemical compound with the molecular formula C8H17N. It is a colorless to pale yellow liquid with a pungent odor, and it is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. 1,2,6-Trimethylpiperidine is also utilized as a solvent and as a corrosion inhibitor in the petroleum industry. It has been shown to exhibit insecticidal and acaricidal properties, making it useful in the development of pest control products. Additionally, this chemical is known for its ability to form stable complexes with metal ions, which has led to its use in analytical chemistry as a complexing agent. However, 1,2,6-trimethylpiperidine is considered to be a hazardous substance, and appropriate safety measures should be taken when handling and storing it.

InChI:InChI=1/C8H17N/c1-7-5-4-6-8(2)9(7)3/h7-8H,4-6H2,1-3H3

Upstream product

• 124-38-9 carbon dioxide 
• 504-03-0 2.6-dimethylpiperidine 
• 50-00-0 formaldehyd 
• 108249-54-3 1,2,6-trimethyl-pyridinium; bromide 

Relevant articles and documents

PROCESS FOR PRODUCING N-METHYL OR N,N-DIMETYL AMINES

A process for producing N-methyl or N,N-dimethyl amines, which comprises using amine compound, nitro-containing compound or nitrile compound as a starting material, carbon dioxide as a methylating agent and hydrogen gas as a reducing agent, and allowing them to react in a sealed reactor for 6 to 48 h in a reaction medium at a reaction temperature of 80 to 180 ° C. in the presence of a composite catalyst, so as to provide N-methyl or N,N-dimethyl amines. The process of the present invention is simple and under relative mild reaction conditions. By means of the process of the invention, the target products can be prepared at low cost with a high yield. The catalysts used have a high catalytic activity and can be separated from the reaction system simply and reused. Furthermore, the whole process of the present invention is environmental-friendly and facilitates the cycling use of carbon dioxide.

Piperidylidene derivatives of carboxy-5H-dibenzo[a,d]cycloheptene

The new 1-alkyl-4-(1, 2, or 3-carboxy-5H-dibenzo[a,d]cyclohepten-5-ylidene)-piperidine compounds are prepared from the corresponding 1, 2 or 3-carboxy-5H-dibenzo[a,d]cyclohepten-5-one by reaction with a Grignard reagent prepared from a 1-alkyl-4-halo piperidine to form an intermediate carbinol, or a 1, 2 or 3-carboxy-5-(1-alkyl-4-piperidyl)-5H-dibenzo[a,d]cyclohepten-5-ol which is then dehydrated to produce the desired 1-alkyl-4-(1, 2 or 3-carboxy-5H-dibenzo[a,d]cyclohepten-5-ylidene)-piperidine, or alternatively by hydrolysis of a 1-alkyl-4-(1, 2 or 3-cyano-5H-dibenzo[a,d]cyclohepten-5-ylidene)-piperidine compound to form the corresponding 1-alkyl-4-(1, 2 or 3-carboxy-5H-dibenzo[a,d]cyclohepten-5-ylidene)-piperidine compound.