669056-35-3

Upstream product

• 858-98-0 3-benzyloxyestra-1,3,5⁽¹⁰⁾-trien-17-one 
• 669056-39-7 3-benzyloxy-16-(N-methyl-N-phenylaminomethylidene)-estra-1,3,5⁽¹⁰⁾-triene-17-one 
• 100-39-0 benzyl bromide 
• 53-16-7 Estrone 
• 669056-34-2 3-benzyloxy-estra-1,3,5⁽¹⁰⁾,16-tetraeno[17,16-e]-2'-(S-benzyl-N-tert-butoxycarbonyl-L-cysteinylamino)pyrimidine 

Downstream Products

• 1199558-89-8 3-benzyloxyestra-1,3,5⁽¹⁰⁾,16-tetraeno[17,16-e]-2'-(N-tert-butoxycarbonyl-L-alanyl-S-benzyl-L-cysteinylamino)pyrimidine 
• 669056-37-5 3-benzyloxy-estra-1,3,5⁽¹⁰⁾,16-tetraeno[17,16-e]-2'-(glycyl-S-benzyl-L-cysteinylamino)pyrimidine 
• 669056-36-4 3-benzyloxy-estra-1,3,5⁽¹⁰⁾,16-tetraeno[17,16-e]-2'-(N-tert-butoxycarbonyl-glycyl-S-benzyl-L-cysteinylamino)pyrimidine 

Relevant academic research and scientific papers

Estrano[17,16-e]pyrimidine-peptide conjugates

The preparation of a steroidal heterocycle linked to the tripeptide Cys-Gly-Cys is described. Initially, an estrane-derived steroidal heterocycle containing an aminopyrimidine ring fused to the 16,17-position of the steroidal nucleus was synthesized. Thereafter, protected amino acids were coupled iteratively by the DCC method, commencing at the amino group of the aminopyrimidine unit.