66923-52-2

Upstream product

• 7597-45-7 3-(4-nitrophenylsulfanyl)-propanoic acid 
• 114426-32-3 3-(4-Nitro-benzolsulfinyl)-propionsaeure 
• 90417-77-9 3-((4-nitrophenyl)sulfonyl)propanenitrile 
• 13113-79-6 sodium 4-nitrobenzenethiolate 
• 90417-47-3 2-cyanoethyl p-nitrophenyl sulfide 
• 1849-36-1 para-nitrobenzenethiol 
• 2937-05-5 4-nitrobenzenesulfonohydrazide 
• 79-10-7 acrylic acid 

Relevant academic research and scientific papers

Synthesis method of 3-sulfonyl propionic acid compound

The invention discloses a synthesis method of a 3-sulfonyl propionic acid compound. The method comprises the following steps: performing reaction by taking substituent sulfonhydrazide and alpha, beta-unsaturated carboxylic acid compounds as raw materials and water as a solvent to produce 3-sulfonyl propionic acid, and performing simple separation after the reaction to obtain the 3-sulfonyl propionic acid. According to the method, the 3-sulfonyl propionic acid can be obtained through one-step reaction, the solvent is environmentally-friendly and the yield is high. The propionic acid compound obtained by one-step direct synthesis is an important medical intermediate, a new method for synthesizing sulfonyl substituent carboxylic acid compound is provided for the field of chemical synthesis.