66933-69-5

Usage

Uses

Used in Pharmaceutical Industry:
4-Pyrrolidin-1-ylpyridine-2-carboxylic acid hydrochloride is used as a cognitive enhancer for the treatment of cognitive impairments and disorders. It is particularly effective in managing conditions such as Alzheimer's disease and dementia, where it helps improve memory, learning, and cognitive function.
Used in Neurological Applications:
In the field of neurology, 4-Pyrrolidin-1-ylpyridine-2-carboxylic acid hydrochloride is used to address various cognitive issues. Its ability to modulate neurotransmitters makes it a valuable tool in enhancing mental performance and supporting brain health.
Used in Off-Label Treatments:
Although not officially approved for these conditions, 4-Pyrrolidin-1-ylpyridine-2-carboxylic acid hydrochloride is used off-label for managing attention deficit hyperactivity disorder (ADHD), anxiety, and depression. Its neuromodulatory effects are believed to provide symptomatic relief in these conditions, although more research is needed to confirm its efficacy and safety for such uses.

InChI:InChI=1/C10H12N2O2/c13-10(14)9-7-8(3-4-11-9)12-5-1-2-6-12/h3-4,7H,1-2,5-6H2,(H,13,14)

Upstream product

• 1001041-22-0 4-(pyrrolidin-1-yl)picolinamide 
• 99586-65-9 4-chloropicolinamide 
• 123-75-1 pyrrolidine 
• 53750-66-6 4-chloro-pyridine-2-carbonyl chloride 

Downstream Products

• 82776-77-0 N-Cyclopentyl-N-(4-pyrrolidin-1-yl-pyridine-2-carbonyl)-benzamide 
• 83728-59-0 N-(4-Nitro-phenyl)-N-(4-pyrrolidin-1-yl-pyridine-2-carbonyl)-benzamide 
• 82776-76-9 N-Pyridin-2-yl-N-(4-pyrrolidin-1-yl-pyridine-2-carbonyl)-benzamide 
• 83728-58-9 N-(4-Pyrrolidin-1-yl-pyridine-2-carbonyl)-N-p-tolyl-benzamide 

Relevant academic research and scientific papers

Synthesis and tuberculostatic activity of novel N′-methyl-4- (pyrrolidin-1-yl)picolinohydrazide and N′-methylpyrimidine-2- carbohydrazide derivatives

The synthesis of N′-methyl-4-(pyrrolidin-1-yl)picolinohydrazide and N′-methyl-pyrimidine-2-carbohydrazide derivatives (5a and 5b) was carried out. These compounds were used as starting materials to obtain methyl N′-methylhydrazinecarbodithioates 6a and 6b

Use of metal complex compounds as catalysts for oxidation using molecular oxygen or air

Use, as a catalyst for oxidation reactions using molecular oxygen and/or air, of at least one metal complex compound of formula (1) wherein Me is manganese, titanium, iron, cobalt, nickel or copper, X is a coordinating or bridging radical, n and m are each independently of the other an integer having a value of from 1 to 8, p is an integer having a value of from 0 to 32, z is the charge of the metal complex, Y is a counter-ion, q=z/(charge of Y), and L is a ligand of formula (2) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and R11 are each independently of the others hydrogen; unsubstituted or substituted C1-C18alkyl or aryl; cyano; halogen; nitro; —COOR12 or —SO3R12 wherein R12 is in each case hydrogen, a cation or unsubstituted or substituted C1-C18alkyl or aryl; —SR13, —SO2R13 or —OR13 wherein R13 is in each case hydrogen or unsubstituted or substituted C1-C18alkyl or aryl; —NR14R15; —(C1-C6alkylene)-NR14R15; —N(+)R14R15R16; —(C1-C6alkylene)-N(+)R14R15R16; —N(R13)—(C1-C6alkylene)-NR14R15; —N[(C1-C6alkylene)-NR14R15]2; —N(R13)—(C1-C6alkylene)-N(+)R14R15R16; —N[(C1-C6alkylene)-N(+)R14R15R16]2; —N(R13)—N—R14R15 or —N(R13)N″R14R15R16, wherein R13 is as defined above and R14, R15 and R16 are each independently of the other(s) hydrogen or unsubstituted or substituted C1-C18alkyl or aryl, or R14 and R15, together with the nitrogen atom linking them, form an unsubstituted or substituted 5-, 6- or 7-membered ring which may contain further hetero atoms. [in-line-formulae][LnMemXp]zYq??(1) [/in-line-formulae]