66978-40-3Relevant academic research and scientific papers
Synthesis of a new scaffold: The 7H,8H-pyrimido[1,6-b]pyridazin-6,8-dione nucleus
Herold, Franciszek,Kalucka, Malgorzata,Krol, Marek,Herold, Joanna,Kleps, Jerzy,Turlo, Jadwiga
, p. 2643 - 2657 (2007)
This paper describes a modified method of preparation of a number of α-aryl-α-(pyridazin-3-yl)-acetonitriles via the C-arylation reaction of the corresponding carbanions of phenylacetonitriles using 3-chloropyridazine derivatives. KOH and DMSO were used i
Efficient large-scale preparation of phenyl 3-pyridazinyl ketone
Heinisch,Langer
, p. 773 - 778 (2007/10/02)
A convenient approach to phenyl 3-pyridazinyl ketone 4 permitting economical large scale preparation is proposed. Commercially available 3,6-dichloropyridazine 1 serves as the starting material in the three-step process.
Preparation of Heteroaryl Phenylmethanes and a 13C and 15N NMR Spectroscopic Study of their Conjugate Carbanions. Rotational Isomerism and Charge Maps of the Anions and Ranking of the Charge Demands of the Heterocycles
Abbotto, Alessandro,Alanzo, Vito,Bradamante, Silvia,Pagani, Giorgio A.
, p. 481 - 488 (2007/10/02)
2-Benzylpyridazine, 4-benzylpyrimidine, 2-benzylpyrimidine and 2-benzylpyrazine, (5-8) have been prepared in order to study their 13C and 15N spectra and those of their conjugate carbanions (1-4).These systems are aza-homologues of the previously reported
Novel thioamide derivatives containing a pyridazine group
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, (2008/06/13)
Novel pyridazine-containing thioamide derivatives of the formula STR1 wherein R1 is STR2 wherein A is hydrogen, methyl, phenyl or mercapto, and B is hydrogen or phenyl; R2 is hydrogen or methyl; R3 is hydrogen, methyl or p
