60906-52-7

Usage

Uses

Given the provided materials, there are no explicit uses listed for Methanone, phenyl-3-pyridazinyl-. However, based on its classification as a pyridazinone derivative with potential pharmaceutical applications, we can infer possible areas of use:
Used in Pharmaceutical Industry:
Methanone, phenyl-3-pyridazinylis used as a pharmaceutical compound for its potential to interact with biological targets, which may lead to the development of new drugs for various medical conditions. Its diverse biological activities suggest that it could be utilized in the treatment of a range of diseases, pending further research and clinical trials.

Upstream product

• 60905-93-3 3-benzyl-pyridazine 
• 53896-49-4 pyridazine-3-carbonitrile 
• 127478-20-0 phenyl(3-pyridazinyl)methanol 
• 140-29-4 phenylacetonitrile 
• 37542-92-0 2-benzylfuran 
• 73535-73-6 2‐(6‐chloropyridazin‐3‐yl)‐2‐phenylacetonitrile 
• 66978-40-3 α-phenyl-α-(pyridazin-3-yl)-acetonitrile 
• 63540-69-2 2-benzyl-2,5-dimethoxy-2,5-dihydro-furan 

Downstream Products

• 60906-54-9 Z-phenyl(3-pyridazinyl)methanone oxime 
• 60906-53-8 E-phenyl(3-pyridazinyl)methanone oxime 
• 127494-99-9 3-α-chlorobenzylpyridazine 
• 127478-23-3 3-(Phenyl-pyrrolidin-1-yl-methyl)-pyridazine 
• 127478-27-7 3-(Phenyl-phenylsulfanyl-methyl)-pyridazine 
• 127478-24-4 3-(Phenyl-piperidin-1-yl-methyl)-pyridazine 
• 127478-28-8 Dimethyl-[2-(phenyl-pyridazin-3-yl-methylsulfanyl)-ethyl]-amine 
• 127478-22-2 Methyl-phenyl-(phenyl-pyridazin-3-yl-methyl)-amine 
• 127478-25-5 4-(Phenyl-pyridazin-3-yl-methyl)-morpholine 
• 127478-26-6 3-[(4-Methyl-piperazin-1-yl)-phenyl-methyl]-pyridazine 
• 180865-22-9 3-benzyl-α-hydroxyiminopyridazine 
• 136489-69-5 3-methoxy-6-(1-phenylethyl)pyridazine 
• 136489-67-3 1-phenyl-1-(3-pyridazinyl)ethyl chloride 
• 136489-68-4 1-phenyl-1-(3-pyridazinyl)ethene 

Relevant academic research and scientific papers

Efficient large-scale preparation of phenyl 3-pyridazinyl ketone

A convenient approach to phenyl 3-pyridazinyl ketone 4 permitting economical large scale preparation is proposed. Commercially available 3,6-dichloropyridazine 1 serves as the starting material in the three-step process.

Telesubstitution and Dismutation Reactions in the Series of Phenyl-3-pyridazinylmethane Derivatives

Reactions of 3-α-chlorobenzylpyridazine (4) with alkoxides have been found to yield 6-substituted or 4-substituted 3-benzylpyridazines (7a-c, 8a-c) rather than the usual ethers (6a-c).Introduction of an electron-donating substituent into the 6-position of the pyridazine nucleus of 4 has been shown to suppress such telesubstitution processes.With phenyl-3-pyridazinylmethanol (3), thermally induced dismutation affording 3-benzylpyridazine (17) and 3-benzoylpyridazine (11) has been observed. Key Words: 3-Pyridazinylmethyl chlorides, reactions with O-nucleophiles / Telesubstitution / Dismutation, thermally induced

REACTION OF METHOXY-N-HETEROAROMATICS WITH PHENYLACETONITRILE UNDER BASIC CONDITIONS

The monomethoxyl derivatives of various ?-electron deficient N-heteroaromatics reacted with phenylacetonitrile in tetrahydrofuran in the presence of sodium hydride to give α-phenyl-N-heteroareneacetonitriles in the yields ranging from 45 to 78percent.On the contrary, the reaction of these methoxyl derivatives with ethyl cyanoacetate or malononitrile under similar conditions was restricted within narrow limits.The synthesis of benzoyl-N-heteroaromatics by the air-oxidation of α-phenyl-N-hetroareneacetonitriles was described additionally.

Pyridazines. L . Syntheses and Reactions of Phenyl(3-pyridazinyl)methane Derivatives

A convenient approach to phenyl(3-pyridazinyl)ketone (6) and phenyl(3-pyridazinyl)methanol (7) is proposed.Reactions of the related diarylmethyl chloride 8 with various N- and S-nucleophiles were found to afford the expected amines 9a-c, 10a-c and thioeth