66982-46-5

Basic information

• Product Name: 3-Phenylthietan-3-ol
• Synonyms: 3-Phenylthietan-3-ol
• CAS NO: 66982-46-5
• Molecular Formula: C₉H₁₀OS
• Molecular Weight: 166.2401
• Mol File: 66982-46-5.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Phenylthietan-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Phenylthietan-3-ol(66982-46-5)
• EPA Substance Registry System: 3-Phenylthietan-3-ol(66982-46-5)

Safety Data

• Hazardous Substances Data: 66982-46-5(Hazardous Substances Data)

Upstream product

• 108-86-1 bromobenzene 
• 22131-92-6 thietane-3-one 
• 100-59-4 phenylmagnesium chloride 

Downstream Products

• 25903-17-7 3-phenyl-2H-thiete 1,1-dioxide 
• 1826-12-6 4-phenyl-thiazole 
• 66982-50-1 3-phenyl-3-hydroxythietane 1,1-dioxide 

Relevant articles and documents

Synthesis of 1-Pyrroline by Denitrogenative Ring Expansion of Cyclobutyl Azides under Thermal Conditions

We herein report an efficient and systematic synthesis of 1-pyrrolines from cyclobutyl azides under thermal and neutral conditions. The reaction proceeded without any additional reagents, and nitrogen was generated as the sole by-product. Furthermore, the generated 1-pyrrolines could be continuously transformed into pyrroles, N-Boc-amines, and oxaziridines in an one-pot manner. (Figure presented.).

Parallel Approaches for the Functionalization of Thietes: α-Metalation versus C-H Activation

For the first time, an approach to 3,4-disubstituted thietes was developed through two complementary paths. While the first one relies on α-metalation, the second is based on direct C-H functionalization. A new library of sophisticated sulfur-containing four-membered rings is described, paving the way to new bioactive analogues and small heterocycle incorporation.