66998-67-2 Usage
Uses
Used in Pharmaceutical and Agrochemical Production:
[[(2-chloroethyl)sulphonyl]methyl]benzene is used as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its chemical properties allow it to be a precursor for the development of sulfones, sulfonyl ureas, and sulfonamides, which are essential components in a range of medicinal and agricultural products.
Used in Organic Synthesis as a Reagent:
In the field of organic synthesis, [[(2-chloroethyl)sulphonyl]methyl]benzene serves as a valuable reagent. Its reactivity and functional groups make it suitable for a variety of chemical reactions, contributing to the formation of complex organic molecules.
Used in Polymer Production as a Crosslinking Agent:
[[(2-chloroethyl)sulphonyl]methyl]benzene is utilized as a crosslinking agent in the production of polymers. Its ability to form covalent bonds between polymer chains enhances the mechanical properties and stability of the resulting polymeric materials.
Used in Biological Applications:
This chemical also exhibits potential in biological applications, such as an enzyme inhibitor, where it can modulate biological processes by interacting with specific enzymes. Furthermore, it serves as a building block in medicinal chemistry, providing a foundation for the development of new therapeutic agents.
Safety Precautions:
It is crucial to handle [[(2-chloroethyl)sulphonyl]methyl]benzene with care due to its lachrymatory properties. It should be used in a well-ventilated area, and individuals working with this chemical should wear appropriate personal protective equipment to minimize exposure and potential health risks.
Check Digit Verification of cas no
The CAS Registry Mumber 66998-67-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,9,9 and 8 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 66998-67:
(7*6)+(6*6)+(5*9)+(4*9)+(3*8)+(2*6)+(1*7)=202
202 % 10 = 2
So 66998-67-2 is a valid CAS Registry Number.
66998-67-2Relevant academic research and scientific papers
BENZOIC ACID COMPOUNDS AND USE THEREOF AS MEDICAMENTS
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, (2008/06/13)
Benzoic acid compounds of the formula STR1 wherein each symbol is as defined in the specification, optical isomers thereof and pharmaceutically acceptable salts thereof; pharmaceutical composition comprising this compound and pharmaceutically acceptable additive; and serotonin 4 receptor agonists, gastrointestinal prokinetic agents and therapeutic agents for various gastrointestinal diseases, which comprise this compound as active ingredient. The compounds of the present invention have high and selective affinity for serotonin 4 receptor, and show agonistic effects thereon. Accordingly, they are useful medications for the prophylaxis and treatment of various gastrointestinal diseases, central nervous disorders, cardiac function disorders, urinary diseases, and the like, as well as useful anti-nociceptors for analgesic use which increase threshold of pain.
MODERN FRIEDEL-CRAFTS CHEMISTRY. XI. CYCLIZATION OF ARYL HALOALKYL SULFONES, ARYLSULFONYLACYL CHLORIDES AND THEIR CORRESPONDING SULFIDES
Abdel-Wahab, Aboel-Magd A.,El-Khawaga, Ahmed M.,El-Zohry, Maher F.,Khalaf, Ali A.
, p. 31 - 44 (2007/10/02)
The sulfone group deactivation for cyclialkylation and cycliacylation reactions in the presence of Friedel-Crafts catalysts was demonstrated in a number of aryl chloroalkylsulfones (1-8) and arylsulfonylacyl chlorides (17a-22a), respectively.As expected, the corresponding arylchloroalkyl sulfides (9-16) and arylmercaptoacyl chlorides (13a-28a) underwent ring-closure reaction in most cases under the same conditions.The ease of cyclization was governed by the ring size, the stability of the attacking carbocation and the nucleophilicity of the aryl moiety.Also, the behaviour of benzyl sulfones (29, 31a, and 32a) and sulfides (33, 34a and 36a) was inconsistent.Noteworthy, the Friedel-Crafts cyclization reaction is thus considered an accessible method for the synthesis of compounds 37-41 and 45, 51.
