67000-45-7

Upstream product

• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 106-93-4 ethylene dibromide 
• 4860-93-9 3-phenyl-1H-pyrazol-5-one 
• 212247-76-2 2-(2-hydroxyethyl)-5-phenyl-1-tosylpyrazole-3-one 

Downstream Products

• 54679-59-3 3-hydroxy-1-methyl-5-phenylpyrazole 
• 212247-91-1 1-methyl-5-phenyl-2-vinylpyrazol-3-one 
• 212247-89-7 2-(2-cyanoethyl)-1-methyl-5-phenylpyrazol-3-one 

Relevant academic research and scientific papers

Phase-transfer catalyzed alkylation and cycloalkylation of 3-substituted-1H-pyrazol-2-in-5-ones in the absence or presence of carbon disulphide

PTC-alkylation of 3-substituted-1H-pyrazol-2-in-5-ones by different organohalogen reagents at 25°C in the presence of tetrabutylammonium bromide as-catalyst was investigated either in the absence or presence of CS 2. This work aims to study the comparative reactivity of N-versus O-versus C-alkylation and cycloalkylation. Copyright Taylor & Francis Inc.

Unambiguous synthesis of 1-methyl-3-hydroxypyrazoles

2,3-Dihydropyrazolo[3,2-b]oxazoles were used as intermediates in a new method for preparation of N1-methyl-3-hydroxypyrazoles. Synthesis of this bicyclic system was achieved either by alkylation of 3-hydroxypyrazole with 1,2-dibromoethane or, with better