6703-30-6 Usage
General Description
(1R,2R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptane-2-carboxylic acid, also known as bornane carboxylic acid, is a bicyclic organic compound with a carboxylic acid group attached to a bicyclo[2.2.1]heptane ring system. It is a colorless, solid compound with a strong odor. It is commonly used as a chiral building block in the pharmaceutical industry for the synthesis of various drugs and other biologically active compounds. Due to its rigid and chiral structure, it is often used as a starting material for the preparation of chiral catalysts and ligands in asymmetric synthesis. Additionally, its unique structure and properties make it a valuable compound for research and development in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 6703-30-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,7,0 and 3 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 6703-30:
(6*6)+(5*7)+(4*0)+(3*3)+(2*3)+(1*0)=86
86 % 10 = 6
So 6703-30-6 is a valid CAS Registry Number.
6703-30-6Relevant articles and documents
Rearrangement approaches to cyclic skeletons. IX. Stereoselective total synthesis of (±)-camphorenone based on a ring-contraction of bicyclo[3.2.1]oct-6-en-2-one. Reliable one-step diazo transfer followed by a Wolff rearrangement
Uyehara,Takehara,Ueno,Sato
, p. 2687 - 2694 (2007/10/03)
A direct diazo transfer reaction to bicyclo[3.2.1]oct-6-en-2-ones and related compounds was accomplished by treatments with 2,4,6-triisopropylbenzenesulfonyl azide and potassium t-butoxide at -78°C in THF. A Wolff rearrangement of the resulting α-diazoketones in the presence of water gave ring-contraction products, bicyclo[2.2.1]heptenecarboxylic acids. Using these two transformations the total synthesis of (±)-camphorenone was achieved stereoselectively, starting from 1-methoxybicyclo[2.2.2]oct-5-en-2-one.