67064-62-4Relevant articles and documents
A regionally selective hydrogenation method for chromium-catalyzed thick cyclic aromatic hydrocarbons and olefins based on magnesium-activated ligands
-
Paragraph 0020, (2022/01/10)
The present invention relates to the field of hydrogenation, specifically to a chromium-activated complex cyclic aromatic hydrocarbons and olefins promoted by magnesium-activated ligands regionally selective hydrogenation method, which is based on the in situ reduction strategy of magnesium, with biimides as ligands, CrCl2 as catalyst precursors, to construct an efficient low-costchromium hydrogenation system, under mild conditions, to achieve unilateral cyclic hydrogenation of thick ring aromatic hydrocarbons and high-selective hydrogenation of olefins. The system of the present invention is suitable for a variety of substrates of fused cyclic aromatic hydrocarbons, such as tetraphenyl, benzoanthracene, pentabenzo and alfalfa and the like. This provides a simple and efficient strategy and pathway for the synthesis of partially saturated thick cyclic aromatic hydrocarbon compounds.
Method for selectively catalyzing and hydrogenating polycyclic aromatic hydrocarbon by virtue of chromium salt/methyl magnesium bromide
-
Paragraph 0028; 0029; 0030; 0031; 0032; 0138; 0139-0142, (2017/10/13)
The invention discloses a method for selectively catalyzing and hydrogenating polycyclic aromatic hydrocarbon by virtue of chromium salt/methyl magnesium bromide. The method comprises the step of carrying out normal temperature stirring reaction on polycyclic aromatic hydrocarbon in an H2 atmosphere by taking chromium salt and methyl magnesium bromide as catalysts, a diimine compound as a ligand and tetrahydrofuran as a solvent, so as to obtain a hydrogenation product. Based on the regulation and control of the diimine ligand and the synergetic catalysis of chromium salt and methyl magnesium bromide, the high-selectivity hydrocarbon of polycyclic aromatic hydrocarbon is realized at the room temperature; and the method has the advantages of low cost, mild reaction conditions, high selectivity and the like, high-temperature harsh conditions are avoided, and precious metal catalysts with relatively high costs are not used. The method is applicable to the hydrogenation of different 2-site, 9-site and 10-site substituted anthracene derivatives and other polycyclic aromatic hydrocarbon substrates.
Photochemical cycloaromatization reactions of ortho-dialkynylarenes: A new class of DNA photocleaving agents
Funk,Young,Williams,Flanagan,Cecil
, p. 3291 - 3292 (2007/10/03)
We are intrigued by the possibility of consolidating the functional elements of the enediyne anticancer antibiotics, thereby simplifying the task of synthesizing potential chemotherapeutic agents which operate by DNA cleavage pathways. Thus, it was envisaged that certain polycyclic ortho-dialkynylarenes would intercalate into DNA and, moreover, the planar π systems might be further exploited by facilitating photochemical, as opposed to thermal, cycloaromatization/cleavage reactions. We report herein on the viability of this photochemical transformation and the resultant new class of DNA photocleaving agents, whose binding and photoactive domains are consolidated, and which generate two reactive sites for subsequent ribose hydrogen atom abstraction(s).