67083-42-5

Upstream product

• 33175-34-7 N-(3,4-dichlorophenyl)-hydroxylamine 
• 95-76-1 m,p-dichloroaniline 
• 99-54-7 3,4-dichloronitrobenzene 

Downstream Products

• 21232-47-3 3,3',4,4'-Tetrachloroazoxybenzene 
• 14047-09-7 3,3',4,4'-tetrachloroazobenzene 
• 126614-95-7 3',4',4-Trichloroazoxybenzene 
• 106-47-8 4-chloro-aniline 
• 614-26-6 4,4'-bis(chloro)azoxybenzene 
• 126614-93-5 3',4',4-Trichloroazobenzene-2-carboxylic Acid 
• 86412-49-9 N-hydoxy-3,4-dichloroacetanilide 
• 126614-94-6 3',4',4-Trichloroazoxybenzene-2-carboxylic Acid 

Relevant academic research and scientific papers

Transketolase Catalyzed Synthesis of N-Aryl Hydroxamic Acids

Hydroxamic acids are metal-chelating compounds that show important biological activity including anti-tumor effects. We have recently engineered the transketolase from Geobacillus stearothermopilus (TKgst) to convert benzaldehyde as a non-natur

Synthesis of 1H-Indazoles from Imidates and Nitrosobenzenes via Synergistic Rhodium/Copper Catalysis

Nitrosobenzenes have been used as a convenient aminating reagent for the efficient synthesis of 1H-indazoles via rhodium and copper catalyzed C-H activation and C-N/N-N coupling. The reaction occurred under redox-neutral conditions with high efficiency and functional group tolerance. Moreover, a rhodacyclic imidate complex has been identified as a key intermediate.

N-Oxidation of arylamines to nitrosobenzenes using chloroperoxidase purified from Musa paradisiaca stem juice

N-Oxidation of arylamines to their corresponding nitrosobenzenes using a new chloroperoxidase purified from Musa paradisiaca stem juice has been examined. The enzymatic characteristics of the stem chloroperoxidase using 4-chloroaniline as substrate were determined. The Km values for 4-chloroaniline and H2O2 were 770 μM and 154 μM respectively, while the pH and temperature optima were 4.4 and 30°C respectively. The substrate specificities of the enzyme for the arylamines 3,4-dichloroamine, p-aminobenzoic acid, p-toluidine, p-anisidine, m-anisidine, p-aminophenol, o-aminophenol and m-aminophenol have been characterized. The feasibility of using concentrated M. paradisiaca stem juice for the specific conversion of 4-chloroaniline to 4-chloronitrosobenzene has been demonstrated. This enzyme can be used for the N-oxidation of other arylamines.

Preparation electrochimique de nitrosobenzenes

The electrosynthesis of nitrosobenzenes from the corresponding nitro compounds occurs in a "redox" electrolysis cell with flowing solution through two consecutive porous working electrodes of opposite polarities; the nitro compound is reduced at the first porous electrode (cathode) and the resulting phenylhydroxylamine is totally oxidized into the nitroso derivate at the second porous electrode (anode).Some examples show the preparation of nitroso derivatives which are soluble in buffered aqueous medium or in alcohol-water medium.