67092-74-4

Basic information

• Product Name: 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-1,3,6-trimethyl-2-oxo-4-phenyl-, ethyl ester
• CAS NO: 67092-74-4
• Molecular Formula: C16H20N2O3
• Molecular Weight: 288.346
• Mol File: 67092-74-4.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-1,3,6-trimethyl-2-oxo-4-phenyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-1,3,6-trimethyl-2-oxo-4-phenyl-, ethyl ester(67092-74-4)
• EPA Substance Registry System: 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-1,3,6-trimethyl-2-oxo-4-phenyl-, ethyl ester(67092-74-4)

Safety Data

• Hazardous Substances Data: 67092-74-4(Hazardous Substances Data)

Upstream product

• 96-31-1 N,N'-Dimethylurea 
• 141-97-9 ethyl acetoacetate 
• 100-52-7 benzaldehyde 
• 123237-03-6 ethyl 6-methyl-4-phenyl-3,4-dihydropyrimidin-2(1H)-one-5-carboxylate 
• 74-88-4 methyl iodide 

Relevant articles and documents

Synthesis, in-vitro α-glucosidase inhibition, antioxidant, in-vivo antidiabetic and molecular docking studies of pyrrolidine-2,5-dione and thiazolidine-2,4-dione derivatives

α-Glucosidase is considered as a therapeutic target for the treatment of type 2 diabetes mellitus (DM2). In current study, we synthesized pyrrolidine-2,5-dione (succinimide) and thiazolidine-2,4-dione derivatives and evaluated for their ability to inhibit

N,N′-Dialkyl-4-Aryl-3,4-Dihydropyrimidinones and Thiones: Ceric Ammonium Nitrate Catalyzed Synthesis and Molecular Structure Determination by X-ray Crystallography

This work presents a microwave assisted solvent-free synthesis of N,N′-dialkyl-4-aryl-3,4-dihydropyrimidinones/thiones in the presence of Ceric Ammonium Nitrate (CAN) via direct condensation of aromatic aldehydes, β-keto ester, and N,N′-dialkylurea/thiour

N1-Alkylated 3,4-dihydropyrimidine-2(1H)-ones: Convenient one-pot selective synthesis and evaluation of their calcium channel blocking activity

It has been found that selective N1-alkylation of 3,4-dihydropyrimidine-2(1H)-ones can be achieved under solvent-less, mild phase transfer catalytic (PTC) conditions with tetrabutylammonium hydrogen sulfate and 50% aqueous NaOH as the catalyst and base, r