67130-66-9 Usage
Uses
Used in Pharmaceutical Research and Development:
6-AMINO-5-(2-CHLORO-ACETYL)-1,3-DIMETHYL-1H-PYRIMIDINE-2,4-DIONE is used as a research compound for exploring its potential biological activities. Its unique structure allows it to be a promising candidate for the development of new pharmaceutical agents.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 6-AMINO-5-(2-CHLORO-ACETYL)-1,3-DIMETHYL-1H-PYRIMIDINE-2,4-DIONE is employed as a building block in the synthesis of pharmaceutical compounds. Its versatile chemical properties enable the creation of diverse drug molecules with potential therapeutic applications.
Used in Drug Discovery:
6-AMINO-5-(2-CHLORO-ACETYL)-1,3-DIMETHYL-1H-PYRIMIDINE-2,4-DIONE is utilized in drug discovery processes to identify novel therapeutic agents. Its unique structure and properties make it a valuable tool for screening and optimization of potential drug candidates.
Used in Chemical Synthesis Industry:
6-AMINO-5-(2-CHLORO-ACETYL)-1,3-DIMETHYL-1H-PYRIMIDINE-2,4-DIONE is used as a key intermediate in the synthesis of various chemical compounds. Its reactivity and functional groups make it suitable for use in the production of specialty chemicals and pharmaceutical intermediates.
Check Digit Verification of cas no
The CAS Registry Mumber 67130-66-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,1,3 and 0 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 67130-66:
(7*6)+(6*7)+(5*1)+(4*3)+(3*0)+(2*6)+(1*6)=119
119 % 10 = 9
So 67130-66-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H10ClN3O3/c1-11-6(10)5(4(13)3-9)7(14)12(2)8(11)15/h3,10H2,1-2H3
67130-66-9Relevant academic research and scientific papers
Synthesis of Hetaryl Pyridinium Salts and Fused 3-Amino-pyrid-2-ones
Rehwald, Matthias,Bellmann, Peter,Jeschke, Torsten,Gewald, Karl
, p. 371 - 378 (2007/10/03)
1-(3-Coumaryl)-pyridinium salts 3 and 1-(3-coumaryl)-tetrahydrothiophenium salts 5 were synthesized from 2-acylphenyl chloro- or bromoacetates 2. 2-Chloro-N1-(3,4-dimethoxyphenyl)-acetamide and substituted 2-chloro-N1-(2-thienyl)-acetamides 8 react with acetyl chloride and pyridine to yield the quinolinyl- and (thieno[2,3-b]pyridin-5-yl)-pyridinium salts 10. Fused thieno[2,3-b]pyridin-ones 19 were formed from N-chloroacetyl-2-aminothiophen-3-carbonitriles 16 with pyridine via Thorpe-Ziegler cyclization and followed by cyclodehydrogenation. In presence of pyridine alkyl 2-chloro-acetylaminobenzoates 21 yield 3-(1-pyridinio)-quinoline-4-olates 23. Zincke-cleavage of 10 and 23 with hydrazinium hydroxide leads to fused 3-amino-pyridine-2-ones 11 and 3-amino-4-hydroxy-quinoline-2-ones 24, respectively. Oxazoloquinolines 25 were synthesized from 24 with acetic anhydride.
